The Powerpuff Girls: Unleashed
Television show information



Based on

The Powerpuff Girls by Craig McCracken

Developed by

Lauren Faust

Voices of

Cathy Cavadini
Tara Strong
Elizabeth Daily

Country of

United States





Craig McCracken (creative consultant)
Lauren Faust
For Cartoon Network Studios:
Brian A. Miller
Jennifer Pelphrey
For Cartoon Network:
Robert Sorcher

Running time

22 min. (approx.)


Cartoon Network Studios


Warner Bros. Television Distribution



Cartoon Network

Original release

May 16th, 2020 - present


Preceded by

The Powerpuff Girls

The Powerpuff Girls: Unleashed is an American animated action-comedy-drama superhero television series serving as a sequel to The Powerpuff Girls by Craig McCracken, being developed by Lauren Faust. It is produced by Cartoon Network Studios and it airs on Cartoon Network since May 16th, 2020.


The girls, now in their teens, are enrolled in Proton Academy for Young Heroes as they begin to be trained by the teachers as they now deal with new villains and life in a whole new school.



  • Blossom Utonium (voiced by Cathy Cavadini) - the leader and the smartest of the trio who is usually shown trying to TBD.
  • Bubbles Utonium (voiced by Tara Strong) - the diztiest and the girliest of the trio who enjoys TBD.
  • Buttercup Utonium (voiced by Elizabeth Daily) - the toughest and most aggressive of the trio who TBD.


  • Professor Utonium (voiced by Tom Kane until 2021 and by Nolan North afterwards) - the Girls' overprotective and caring creator/father who now works as a teacher at Proton Academy while warning them about the challenges of being a teenage hero and any kind of possible danger or menace.
  • Headmistress Adrian Proton (voiced by Olivia d'Abo) - the serious headmistress of Proton Academy for Young Heroes who has a rather TBD sense of respect for the Powerpuff Girls and believes that they are destined to become TBD.
  • Ms. Keane (voiced by Jennifer Hale) - the Girls' motherly and understanding former kindergarten teacher who was admitted into the Academy as she now teaches TBD.
  • Luke Wesley/Crusher (voiced by Jason Spisak) - a reckless student who can destroy any type of material and TBD.
  • Belle Larson/Invisibelle (voiced by Grey Griffin) - a geeky student who can turn invisible and TBD.
  • Biff Wellington/Mirror (voiced by Josh Keaton) - a charismatic student who can duplicate himself as he uses it to TBD.
  • Liz Telsa/Velox (voiced by Hynden Walch) - a spunky student who is able to run at superhuman speed as TBD.
  • Apollo Dipper/Gamma Ray (voiced by James Arnold Taylor) - a TBD student who can move his energy TBD.
  • Aimee Dubois/Miss Magical (voiced by Kath Soucie) - a friendly French student who is an old friend of the trio and is now an exchange student as TBD.
  • Mason Midgley/Stinger (voiced by Greg Cipes) - TBD
  • Major Glory (voiced by Rob Paulsen) - the Powerpuff Girls' brave and heroic idol who inspired them to join the Proton Academy and is TBD.


  • Dr. Olivia Beck/The Doctor (voiced by Laura Bailey) - a mentally insane scientist who wants revenge on the Girls after losing her job and home due to her being in the crossfire between a fight between them and a villain and wants them dead, believing that they are menaces to the world.
    • Mainframe (voiced by Max Mittelman) - an intelligent hacker who is an expert at hacking technology.
    • Pyronica (voiced by Mae Whitman) - a seductive criminal who is able to burn TBD.
    • Electric Elris (voiced by Xander Mobus) - a charismatic criminal who can summon electricity and is TBD.
    • She-Plant (voiced by Melissa Fahn) - an insane criminal who TBD.
  • Mojo Jojo (voiced by Roger L. Jackson) - a mad genetically-mutated chimpanzee who used to be Utonium's partner until he created the accident that created the Powerpuff Girls, making him into what he is today, as he is willing to destroy them.
    • Brash (voiced by Amanda Leighton) - Mojo Jojo's atempt to replicate the Powerpuff Girls formula and create a perfect match for them, being completely poweful and TBD.
  • Him (also voiced by Tom Kane until 2021 and by Gregg Berger afterwards) - a sadistic demon who is the Powerpuff Girls' most powerful enemy since he's able to control reality and TBD.
  • Fuzzy Lumpkins (voiced by Jim Cummings) - a cranky hillbilly creature who hates the ones who TBD.
  • Princess Morbucks (also voiced by Jennifer Hale) - a spoiled and rather arrogant rich girl who forced herself into the Academy in order to keep her plans to become a Powerpuff Girl, even if it implies destroying them.
  • Sedusa (also voiced by Jennifer Hale) - a seductive criminal who TBD.
  • Professor Chronotech (voiced by Alex Hirsch) - a former science teacher for the Academy who grew envious of Utonium and wants to kill him by using time travel TBD.
  • The Ultimo League, consisting of:
    • Ultra Dynamic Man (voiced by Sam Daly) - a selfclaimed superhero who leads the Ultimo League as he and his teammates try to replace the Girls as heroes of Townsville.
    • Dark Avenger (voiced by Dante Basco) - TBD
    • The Monkey King (voiced by Patrick Warburton) - TBD
    • Sonic Boom (also voiced by Grey Griffin) - TBD
    • Houdina (voiced by Ashley Johnson) - TBD
    • The Gnat (voiced by Dee Bradley Baker) - TBD
  • Tom Shelly (voiced by TBD) - TBD
  • Legion of Evil People, consisting of:
    • Dr. Herman Zaule (voiced by Jeffrey Combs) - a hammy yet villainous mad scientist who TBD.
    • Crab Man (voiced by Paul F. Tompkins) - a criminal wearing a crab outfit who TBD.
    • Mandy Quinn (also voiced by Tara Strong) - a disgraced model who has begun turning random people into mannequins for an unknown evil purpose.
    • Barbara Flice/Inflata (voiced by [Ms. Fanservice as well]) - a criminal who is capable to expand her body into gigantic proportions.
    • Metal Leaper (voiced by Khary Payton) - an egocentric criminal who is wearing a metal armor and can leap giant heights.
    • General Krieg (voiced by Rodger Bumpass) - a WWII-themed criminal who TBD.
    • Lady Soprano (voiced by Kate Miccuci) - a TBD criminal who can control people by using her singing voice to do TBD.
    • The Beekeeper (voiced by Tom Kenny) - a TBD criminal who is obsessed bees TBD.


See List of The Powerpuff Girls: Unleashed episodes.


Critical response

This series received generally positive reviews from critics, while it was a critical acclaim for both viewers and fans of the original 1998 series, being praised for TBD.

Shared universe

See CN Futureverse.

After initial speculation, the series was revealed to be part of a larger project that connects it to Dexter's Laboratory and The Grim Adventures of Billy and Mandy to modernize and reimagine the characters.


See The Powerpuff Girls: Unleashed/Tropes.


  • This series turns The Powerpuff Girls into the third Cartoon Network original franchise to feature a timeskip sequel with the other two being Ben 10 and Steven Universe.
  • Rather than following the same art style as the 1998 series, the series opts to use an anime-like art style, being strongly inspired by the ones from Powerpuff Girls Z and DC Super Hero Girls.
    • Due to that and being set in a hero academy, the series is nicknamed "My Powerpuff Academia" and "The Sky High of CN" by some fans.
  • Although Craig McCracken is not directly involved in the show, unlike the 2016 reboot, he gave his blessing since it's being handled by people who worked on the original show (including his wife) alongside some new writers who were actual fans of it, aside from the fact he still acts as executive producer and creative consultant for it.
  • Due to them being older, the Girls' voices are notably different and sound more mature as well.
  • Only five primary villains from the original series return in this sequel, while Professor Utonium and Ms. Keane are the only returning supporting characters in this, focusing more on newer villains and new concepts as well.
  • Due to Tom Kane suffering a stroke in late 2020 that deprived him of his ability to speak, his roles were recasted by Season 2.
    • The first episodes produced following the recast would include a caption preceding the closing credits saying "Get well soon, Tom".
  • Variant:
    • Cartoon Network Studios: The custom animation features the Girls cheering and high-fiving each other after defeating a villain, preceded by Blossom saying "Good job, girls!".
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