Mouse in Space is an online video series launched in 2016, based on the original recurring segment from the animated series The Shiresland Show. It stars Michelle Mouse as First Mate Michelle, George Mouse as Captain George Mouse, and Cheddar Board Clarence on board the spaceship Swinetrek. The updated series features a CGI render of the ship, with the crew in their original uniforms.
- Charles Martinet as George Mouse
- Tress MacNeille as First Mate Michelle
- Dwayne Hill as Cheddar Board Clarence and the Narrator
- Eric Bauza as Martin and Rogor