Marvel Zombies: The Video Game is an American horror video game based on Marvel Comics. It is heavily inspired on the Marvel Zombies comic book series.
When New York gets devastated by a zombie virus outbreak, Mary Jane Watson now has to navigate the streets of New York now dealing with numerous zombies including zombified super humans.
- Mary Jane "MJ" Watson (voiced by Danica McKellar) - The main protagonist, and one of the survivors of the zombie virus outbreak. Her tragedy begun when she witnessed her mother and aunt Anna getting killed and Peter Parker/Spider-Man getting infected and turned into a zombie, all by the hands of a zombified Black Cat.
- Nicholas "Nick" Fury (voiced by Khary Payton) - The only non zombified agent of S.H.I.E.L.D. who leads a safe haven for survivors.
- Peter Quill/Star-Lord (voiced by Jason Spisak) - The half-human, half-alien former leader of the Guardians of the Galaxy. His tragedy begun after Gamora was infected during the outbreak and turned into a zombie, killing Rocket and Groot and infecting Drax as well, forcing Quill to kill her. He is shown to be Mary Jane's new lover, and they sympathize with each other over their losses.
- Cassandra "Cassie" Lang (voiced by Katie Leigh) - The 6-year-old daughter of Scott Lang/Ant-Man. She is initially traumatized over father's death by the hands of a zombified Hank Pym, but is comforted by MJ, whom she grows close to view as a new mother.
- Sinthea Schmidt (voiced by Erica Luttrell) - The main human antagonist and leads a group of survivors out to kill other survivors of the epidemic.
- Reed Richards/Mr. Fantastic (voiced by C. Thomas Howell) - The main zombie antagonist and the former leader of the Fantastic Four who miraculously kept most of his intellect, yet his mind got twisted in a terrifying hungry way. His tragedy begun when he lost his sanity following his teammates' and children's infection and soon became a zombie himself at the hands of his family.
- Peter Parker/Spider-Man (voiced by Sam Riegel) - Mary Jane's first lover and formerly a superhero before he was infected by Black Cat.
- Tony Stark/Iron Man (voiced by Matthew Mercer) - TBD
- Steve Rogers/Captain America (voiced by TBD) - TBD
- Kamala Khan/Ms. Marvel (voiced by Kathreen Khavari) - The former leader of the Champions and a young Inhuman with Size-Shapeshifting powers. She was infected by a zombified Spider-Man after trying to stop him from devouring her family.
- Jennifer "Jen" Walters/She-Hulk (voiced by Grey Griffin) - TBD
- Felicia Hardy/Black Cat (voiced by Marisha Ray) - Formerly a cat burglar who had a complicated relationship with Spider-Man before she was zombified. She is responsible for infecting Spider-Man and killing Mary Jane's mother and Aunt Anna.
- Generic Zombies (voiced by various) - regular civilians who are regular enemies.
- Henry "Hank" Pym (voiced by TBD) -
- Thor Odinson (voiced by Dave B. Mitchell) - TBD
- Bruce Banner/Hulk (voiced by Fred Tatasciore) - TBD
- J. Jonah Jameson (voiced by Mark Hamill) - a loud-mouthed reporter who is the first zombie MJ kills in game and one of the notable characters in the game who is a basic enemy and not a boss.