Cartoon Mayhem: Russell and Zoe Chronicles is a flash adult animated black comedy action series developed by DHX Media, Chernin Entertainment and 20th Century Fox Television for Comedy Central. It is based on the 2024 box office hit, Cartoon Mayhem.
The series is rated TV-MA for crude sexual humor and content, strong language, some bloody violence, sexual jokes and drug use with some episodes being rated TV-14.
Russell and Zoe and their friends have raunchy adventures.
- Samuel Vincent as Russell Ferguson, a hedgehog from Littlest Pet Shop
- Grey Griffin as Zoe Trent, a dog from Littlest Pet Shop.
- Kevin Michael Richardson as Lavash, a lavash from Sausage Party.
- Tara Strong as Lagan Fuller, a 11th grade human from The Chronicles of Collin the Speedy Boy and the leader of the Cartoon Punishers.
- Phil LaMarr as Douche, a hygiene product from Sausage Party and main antagonist of the show.
- Greg Baldwin as Aku, a evil demon that is bent on turning the world into his own image.
- Tom Kenny as Lumpy, a blue moose from Happy Tree Friends and is one of the Cartoon Punishers; Caillou, a preschooler from the series of the same name who is one of the Cartoon Punishers.
Animation for the series was provided by 9 Story Entertainment.
- This is the second Cartoon Mayhem media to feature movie characters, after Cartoon Mayhem: Going Reloaded.