The Miss Wisteria Show

The Miss Wisteria Show (Zā Wisteria-San Miseru) is a Japanese Anime series created by Waku Yaniko and one of his few works not based on one of Yaniko's mangas (although Randel and Snitch started out as a manga series). This anime ran from April 22, 1989-November 30, 1993.

Wisteria
Wisteria Namiko is a 80-year old woman with incredibly poor eyesight and, due to this, always causes destruction wherever she goes but when she is in trouble, her dog Naru would always save her without her knowing.

The Five Aliens
Teto, Cannie, Ma, Gura and Zekiro ran away from Planet Nuko for insulting Mayor Takaru and landed in a recently-bought house on Planet Earth where they met two pre-teen siblings named Takashi and Hacomimi Fukunatiro.

Randel and Snitch
Randel and Snitch are two animals that live in a cottege in a forest-like town and, despite their differences, the amount of misadventures they have and Randel's short temper, they still love each other.