The Amazing Adventures of Spider-Man

"The Amazing Adventures of Spider-Man" is an animated series that stays true to the comic book series, retelling original stories but has some aspects from the fan favorite animated series, The Spetacular Spider-Man.

Main

 * Josh Keaton - Spider-Man/Peter Parker
 * Susanne Blaksee - Madame Web, May Parker
 * Vannessa Marshall - Mary Jane Watson, Jean DeWolff
 * Daran Norris - J. Jonah Jameson, John Jameson, Richard Parker, Alistair Smythe, Beetle/Abner Jenkins, Venom, Anti-Venom
 * James Arnold Taylor - Harry Osborn/New Goblin
 * Lacey Chabert - Gwen Stacy
 * Clancy Brown - George Stacy, Dr. Farley Stillwell
 * Steven Weber - Norman Osborn

Supporting

 * Edward Asner - Ben Parker
 * Tricia Helfer - Black Cat/Felica Hardy
 * Matt Lanter - Flash Thompson, Kaine Parker
 * Grey DeLisle - Sally Avril, Betty Brant, Michele Gonzales
 * Masasa Moyo - Debra Whitman
 * Michael T. Wiess - Ben Urich
 * Kath Souice - Mary Parker, Ann Watson, Dr. Martha Connors
 * Kevin Michael Richardson - Joesphe "Robbie" Robertson
 * Cree Summer - Glory Grant
 * Tim Russ - Prowler/Hobbie Brown
 * Greg Eagles - Randy Robertson
 * Quinton Flynn - Ned Leeds, Eddie Brock
 * Gabrielle Carteris - Silver Sable/Silver Sablinova
 * Mae Whitman - Carlie Cooper
 * Tara Strong - Dr. Ashley Kafka, Liz Allan
 * John DiMaggio - Crusher Hogan
 * Max Burkholder - Billy Connors
 * Thomas F. Wilson - Stan Carter
 * James Remar - Walter Hardy
 * Audrey Wasilewski - Lydia Hardy
 * Ogie Banks - Rocket Racer/Robert Farrell
 * Mark Hamill - Ezekiel Sims
 * Dee Bradley Baker - Dr. Curt Connors
 * Neil Patrick Harris - Scarlet Spider/Ben Riley
 * Steven Blum - Puma/Thomas Fireheart

Villians

 * Dee Bradley Baker - The Lizard, Vermin/Edward Whelan
 * Armin Shimmerman - Green Goblin
 * Rick D. Wasserman - Sandman/Flint Marko, The Burglar
 * Peter Lurie - Rhino/Aleksei Sytsevich/Alex O'Hirn, Dr. Mendel Stromm
 * John Kassir - Scorpion/MacDonald "Mac" Gargan, Jack O'Lantern/Jason Philip Macendale
 * Gregg Berger - Mysterio/Quentin Beck
 * Diedrich Bader - Shocker/Herman Schultz, Big Wheel/Jackson Weele
 * Dwight Schultz - Vulture/Adrien Toomes
 * Mark Hamill - Hobgoblin/Roderick Kingsley, Spot/Dr. Jonathan Ohnn, Morlun
 * Charlie Adler - Carnage/Cletus Kassidy
 * Christopher Daniel Barnes - Kaine Parker
 * George Takei - Mister Negative/Martin Li
 * Dorian Harewood - Tombstone/Lonnie Thompson Lincoln
 * Jim Cummings - Kraven The Hunter/Sergei Kravenoff, Boomerang/Frederick "Fred" Myers, Kingpin/Wilson Fisk
 * John DiMaggio - Hammerhead/Joseph Lorenzini, Juggernaut/Cain Marko, Grizzly/Maxwell Markham, Demogoblin, Man-Wolf
 * Peter MacNicol - Doctor Octopus/Otto Octavius
 * Thomas F. Wilson - Electro/Max Dillon
 * Brad Garrett - Hydro-Man/Morris Bench
 * Dan Castellaneta - Chameleon/Dmitri Anatoly Nikolayevich Smerdyakov Kravinoff
 * Brian George - Jackal/Dr. Miles Warren
 * Andrew Kishino - Molten Man/Mark Raxton
 * Philip Proctor - The Tinkerer/Phineas Mason
 * Adrian Pasdar - Swarm/Fritz von Meyer
 * Richard McGonagle - Spencer Smythe
 * Nick Jameson - Morbius/Dr. Michael Morbius
 * Miguel Ferrer - Silvermane/Silvio Manfredi
 * Mark Rolston - Black Rose/Richard Fisk
 * Dawnn Lewis - Calypso/Calypso Ezili
 * Grey DeLisle - Scream/Donna Diego

Enforcers

 * Dee Bradley Baker - Fancy Dan/Daniel Brito
 * John DiMaggio - The Ox/Raymond Bloch
 * Keith Szarabajka - Montana/Jackson W. Brice
 * James Arnold Taylor - The Big Man/Fredrick Foswell

Guest Heroes

 * John DiMaggio - /James "Logan" Howlett, The Thing/Ben Grimm, The Hulk/Bruce Banner, War Machine/James Rhodes, Rocket Raccoon
 * Marc Worden - Iron Man/Tony Stark
 * Tim Curry - J.A.R.V.I.S.
 * Brian Bloom - Daredevil/Matthew Murdock
 * Diedirch Bader - Nova/Richard Rider, Iron Fist/Danny Rand, Clay Quartermain
 * Wally Wingert - Mr. Fantastic/Reed Richards
 * Quinton Flynn - Human Torch/Johnny Storm
 * Grey DeLisle - Invisible Woman/Susan Storm-Richards
 * Charlie Adler - Howard the Duck, Deadpool/Wade Wilson
 * Maria Canals-Barrea - White Tiger/Angela Del Toro, She-Hulk/Jennifer Walters
 * Daran Norris - Captain America/Steve Rogers
 * Gary Anthony Williams - Luke Cage
 * Troy Baker - Moon Knight/Marc Spector
 * Leonard Nimoy - Uatu the Watcher
 * J.G. Hertzler - Nick Fury
 * Ron Perlman - Cable/Nathan Summers

Guest Villians

 * Tim Curry - Doctor Doom/Victor Von Doom
 * Charlie Adler - M.O.D.O.K./George Tarlenton, Technovore, Super-Skrull/K'lrt
 * John DiMaggio - Whiplash/Anton Vanko, Galactus, Red Hulk, Abomination/Emil Blonsky, Ronan the Accuser, The Supreme Intelligence
 * James Arnold Taylor - Magneto/Erik Lensherr
 * Clancy Brown - Red Skull/Johann Schimidt
 * J.G. Hertzler - Taskmaster/Tony Masters
 * Keith Ferguson - Mr. Sinister/Nathanel Essex
 * Maurice LaMarche - Ultron