Similarities to the Powerpuff Girls

Alex as Blossom

 * Both are considered smart.
 * Both wore pink, at some point.
 * Both are vain beauties.
 * Both have cried, at some point because of the spoiled brat.
 * Both have orange hair, although Alex's hair is dyed.

Elisa as Buttercup

 * Both girls were considered to be antagonistic.
 * They have a tomboy attitude.
 * Both have dark hair.
 * Both have a grumpy side.

Christian as Bubbles

 * Both are younger looking characters.
 * Both were blonde.
 * Both cry, constantly.
 * They both talk like younger children.
 * Both have easily suspected the culprit:
 * Bubbles suspected Sudusa for her crimes
 * Christian suspected Alex to check for food (i.e. McDonald's and Panda)

Lorna as Sedusa

 * Both were antagonistic mothers.
 * Both had problems with the main three protagonists.
 * Both are considered evil and wicked.

Vince as Mojo Jojo

 * Both are evil.
 * Talk in a foreign accent.
 * Both hate the trio.

Stacy as Professor Utonium

 * Both people are smart
 * Both care for their (not-quite) kids, like a good parent.
 * Both are single.
 * Both of their relationships are broken up.