The Mightypuff Girls

 is an American action-adventure-comedy superhero comic book series based on , being published by since TBD 20??.

Synopsis
Set in a distant future in the City of Qwertysville, three young girls join forces to face several threats that haunt their hometown.

Main

 * Mecha Utonium - the leader of the trio and Blossom's descendant who is extremely intelligent, providing the team with her own gadgets.
 * Mena Utonium - the ditziest of the trio and Bubbles' descendant who is obsessed with cute animals and fashion.
 * Meteor Utonium - the strongest of the trio and Buttercup's descendant who often gets into trouble due to her TBD.

Supporting

 * Prof. Chase Utonium - a scientist who is the Mightypuff Girls' creator/father and Professor Utonium's descendant, being very caring and protective of them.
 * The Mayor of Qwertysville - the Mayor of Townsville's descendant who TBD.
 * Ms. Sasha Bellum - the Mayor's assistant and Ms. Bellum's descendant who TBD.
 * Ms. Kristen Keane - the Mightypuff Girls' teacher at Qwertysville High School and Ms. Keane's descendant who TBD. It's later revealed she's dating their father.
 * Carolyn Snyder - the Mightypuff Girls' best friend and Robin Snyder's descendant who TBD.

Antagonists

 * Mojo Jupiter - a genetically modified chimpanzee and Mojo Jojo's descendant who TBD.
 * It - a powerful demon and Him's descendant who aims to destroy TBD.
 * Duchess Megabytes - TBD
 * Lord Silico - TBD
 * Fluffy Lumpkins - TBD
 * The Cygreen Gang, consisting of:
 * Spade Copular - TBD
 * Jasmine "Serpent" Ingleberry - TBD
 * Armando "Lil' Armando" de la Guerra - TBD
 * [Grubber] - TBD
 * Daniel "Big Danny" Williams - TBD
 * [Sedusa] - TBD
 * The Amoeba Gang, consisting of:
 * Extreme Leader - TBD
 * [Junior] - TBD
 * [Slim] - TBD

Trivia

 * This comic has a similar premise to Loonatics Unleashed.