Me and My Guardian Angel

 was an American animated adventure-fantasy-comedy television series, being created by. It was produced by Walt Disney Television Animation and it aired on Disney Channel from May 20th, 2000 until June 16th, 2006.

Synopsis
A good-natured but overprotective and rather clumsy guardian angel is sent to protect a rebellious teenage boy who often gets in trouble as they get engaged in a series of shenanigans while dealing with odd events.

Main

 * /Danny Marshall/ (voiced by Jason Marsden) - a rebellious teenage boy who befriends Lena and often engages in several misadventures with her, even if she disagrees with some of his ideas, as he likes her company and even admitted she's "the girl of my dreams".
 * /Lena Sapien/ (voiced by Kath Soucie) - a good-natured but overprotective and rather clumsy guardian angel who is assigned to guard Danny, often trying to get him away from danger, using magic to pass as a "mortal", as she slowly develops a crush on him.

Supporting

 * Evan and Janice Marshall (voiced by Jess Harnell and Candi Milo, respectively) - Danny's friendly and caring parents who are fond of Lena and like the idea of her hanging out with him to get him away from trouble, despite being unaware of her divine origins.
 * The Great One/Grant Sapien (voiced by Brad Garrett) - the stern head of the Great Plains and Lena's father who assigns her to protect Danny from any trouble, even if sometimes he worries about her lack of experience about the mortals' behavior.
 * Azrael (vocal effects by Dee Bradley Baker) - an angelic cat who is mainly the Great One's cat as he is extremely frightened at anything.
 * The Mother/Claire Sapien (voiced by Susanne Blakeslee) - Lena's eccentric but caring mother who helps the Great One to manage the Great Plains while teaching her about the wonders and dangers that the mortals' world brings.
 * Timothy Oldring (voiced by Will Friedle) - a teenage boy who is Danny's best friend and is just as rebellious as him.
 * Nathan Platt (voiced by Charlie Schlatter) - a shy teenage boy who sometimes falls victim into Danny's shenanigans.
 * Carly Rannells (voiced by Nika Futterman) - an athletic teenage girl who is smitten with Timothy as she befriends Lena and is willing to TBD.
 * Sara Davis (voiced by Hynden Walch) - a gothic teenage girl who prefers to stay away from people rather than hanging out with them, although she is fond of Nathan and tries to bond with him.
 * Ms. Jessica Marvins (voiced by Grey DeLisle) - a cynical History teacher who is often suspicious of Lena due to her weird behavior and has a certain dislike of Danny due to his rebellious behavior.
 * Bobby Ferr (voiced by Rodger Bumpass) - a chill and understanding counselor who is one of the few people who are comprehensive about Danny's shenanigans as he is often suggesting TBD.
 * Elaine Marshall (voiced by April Winchell) - a kind-hearted elderly who is Danny's grandmother and Evan's mother.
 * CrunchBeard (voiced by Bill Farmer) - a fictional loud yet skilled pirate character who is the main character of the video game Danny got addicted to, CrunchBeard vs. the Vegetable Monsters.
 * Claw (voiced by Billy West) - a fictional parrot character who follows CrunchBeard throughout the game and is extremely naggy.
 * Mosquito Allen (voiced by Tom Kenny) - an fictional immature and loud mosquito character who is the main protagonist of Mosquito Allen.
 * Equine Kelmer (voiced by Daran Norris) - a fictional mature horse who Mosquito Allen likes to annoy.
 * Maisie Ironyear (also voiced by Kath Soucie) - a fictional spunky and courageous heroine who is the lead character of Super Action Force, inspiring Lena to become her own heroine.
 * Jacob Taylor (voiced by Quinton Flynn) - an immature kid who, along with Danny and Timothy, was forced to become a scout at a summer camp as he often tries to escape the camp.
 * Jacob Taylor (voiced by Quinton Flynn) - an immature kid who, along with Danny and Timothy, was forced to become a scout at a summer camp as he often tries to escape the camp.
 * Jacob Taylor (voiced by Quinton Flynn) - an immature kid who, along with Danny and Timothy, was forced to become a scout at a summer camp as he often tries to escape the camp.

Antagonists

 * The Cold One (voiced by Mark Hamill) - the ruler of the Bad Bad Plains who plots to take over the mortals' world by corrupting everything into his personal kingdom.
 * Claude (voiced by Richard Steven Horvitz) - an extremely narcissistic demon who is trusted to be in charge of a special demonic task, trying to make Lena to quit being a Guardian Angel.
 * Lily (voiced by Elizabeth Daily) - a punky demon who disguises herself as a normal teenage girl to seduce Danny and separate him from Lena.
 * Chad (voiced by Corey Burton) - a demon who gave Nathan demonic powers mainly because he thought it would be pretty funny to see.
 * Flake, Icico and Blizz (voiced by Jim Cummings, Jeff Bennett and Jeff Bergman, respectively) - three demons who all have appearances of snowmen as they like to cause chaos and mischief.
 * Rutch (voiced by Dee Bradley Baker) - a mischievous demon who can turn himself into insects, with cockroaches being his favorite insects to turn into.
 * Stacy Simmons (voiced by Tara Strong) - a loud-mouthed teenage girl who dislikes Danny and the things he does as she often tattletales on him, aside from finding Lena a "freak".
 * Philly Carlson (voiced by Kevin Michael Richardson) - a nerdy student who just moved as he wants to steal Lena from Danny after learning she is a guardian angel.
 * Madelene Chaney (voiced by Kat Cressida) - a creepy little girl who kidnapped Lena to be "her guardian angel".
 * Samuel Marsden (voiced by Maurice LaMarche) - a security guard of the school who once noticed Danny sneaking into the school at night and has tried to catch him.
 * Counselor Mitch Harrington (voiced by Roger L. Jackson) - a strict man who is the counselor of the summer camp as he has a zero tolerance for kids attempting to escape from the camp.
 * The Horde of Squirrels (vocal effects by Dee Bradley Baker) - a wild pack of squirrels who raided Danny and his family's home.
 * The Horde of Squirrels (vocal effects by Dee Bradley Baker) - a wild pack of squirrels who raided Danny and his family's home.

Episodes
See List of episodes.

Tropes
See /Tropes.

Trivia

 * As stated on the show, Danny is 14 and Lena is 216 (physically 16).
 * Despite the use of some divine mythology, the series doesn't add any religious connections, since its developers wanted to focus more on the comedy.
 * As stated on the series, there's two types of angels: the ones that are the souls of deceased people and the ones who were born into it as such like Lena's case.
 * Same with the demons.