The Powerpuff Squirrel

The Powerpuff Squirrel is an American action comedy-drama animated series that is a spin-off to the original Powerpuff Girls.

Synopsis
The series stars Bullet, a squirrel who has superpowers of the Powerpuff Girls, thanks to Bubbles who gave her Chemical X. Unlike the girls who fight crime and monsters in Townsville, Bullet has to save her forest home from natural disasters and predatory villains, with a little help from her friends.

Main

 * Bullet (voiced by Hynden Walch) - An eastern grey squirrel with superpowers.
 * Buddy (voiced by Billy West) - An eastern cottontail who is one of Bullet's friends.
 * Reynard (voiced by Danny Jacobs) - A red fox who is one of Bullet's friends. He is also Buddy's best friend, even though he is a predator (and foxes like him are omnivores).
 * Kyle (voiced by Adam McArthur) - An American kestrel who is one of the few birds of prey that Bullet befriended with, due to his small size.
 * Paige (voiced by Melissa Fahn) - A peregrine falcon who lives in the city of Townsville.

Supporting

 * Blossom (voiced by Cathy Cavadini) - The commander and leader of the trio.
 * Bubbles (voiced by Tara Strong) - The joy and the laughter of the trio.
 * Buttercup (voiced by Elizabeth Daily) - The toughest fighter of the trio.
 * Professor Utonium (voiced by Tom Kane) - The girls' father.
 * Ms. Keane (voiced by Jennifer Hale) - The girls' teacher and Professor Utonium's love interest.
 * Dexter (voiced by Candi Milo) - The boy genius and Blossom's boyfriend.
 * Dee Dee (voiced by Kathryn Cressida) - Dexter's loving and caring sister who's also a ditz.
 * Beau (voiced by Pamela Adlon) - Dee Dee's boyfriend and Dexter's best friend.
 * Finn (voiced by Josh Keaton) - A southern flying squirrel.
 * Woodston (voiced by Jeff Bennett) - A wood duck drake.
 * Doris (voiced by Nika Futterman) - A wood duck hen.
 * June (voiced by Nicole Sullivan) - A blue jay who is the forest's most famous news reporter.
 * Rhett (voiced by Troy Baker) - A common raven.
 * Duke (voiced by Khary Payton) - A white-tailed buck.
 * Duchess (voiced by Kath Soucie) - A white-tailed doe.
 * Mighty Bill (voiced by Kevin Michael Richardson) - A bull American bison who is the leader of his bison herd.
 * Mayor McTurkey (voiced by Tom Kenny) - A wild turkey who is the mayor of the forest.
 * Brody (voiced by John DiMaggio) - A Canadian beaver.
 * Armaruq (voiced by Cam Clarke) - A grey wolf who is the leader of his wolf pack.
 * Edgar (voiced by Jonathan Adams) - A bald eagle who is Kyle's brave and heroic idol.
 * Quincy Quill (voiced by Greg Cipes) - A North American porcupine.
 * Barry (voiced by Richard Steven Horvitz) - An American black bear.
 * Badge (voiced by Grey DeLisle) - An American badger.
 * Vivienne (voiced by Kimberly Brooks) - A red fox who is Reynard's love interest.
 * Maria (voiced by Mae Whitman) - A trumpeter swan.
 * Cubby (also voiced by Elizabeth Daily) - A cougar cub.
 * Perline (voiced by Ashley Johnson) - A cougar who is Cubby's mother.
 * Wilson (also voiced by Tom Kenny) - A groundhog.
 * Serenity (voiced by Laura Bailey) - A striped skunk.
 * Sheriff Paco (also voiced by Tom Kane) - A black-tailed prairie dog.
 * Raulo (voiced by Phil Morris) - An American robin.
 * Olva (also voiced by Jennifer Hale) - A northern spotted owl.
 * Floyd (also voiced by Tara Strong) - A red fox cub who is Reynard's nephew.
 * Hector (also voiced by Jeff Bennett) - A mustang stallion.
 * Mason (voiced by Bill Fagerbakke) - A bull moose.
 * Mr. Gander (voiced by Daran Norris) - A Canada goose.
 * Oretta (voiced by Lara Jill Miller) - A North American river otter.
 * Chris (voiced by Benjamin Diskin) - An eastern chipmunk.
 * Benny (voiced by Rodger Bumpass) - A great blue heron.
 * Flint (unvoiced) - A ruby-throated hummingbird who speaks in hums.
 * Kimmy (also voiced by Tara Strong) - A belted kingfisher.
 * Dr. Pecky (voiced by Nolan North) - A pileated woodpecker doctor.
 * Hare Hopdini (voiced by Dana Snyder) - A snowshoe hare magician.
 * Pablo (voiced by James Arnold Taylor) - An Atlantic puffin.
 * Paul (voiced by Matthew Lillard) - An American white pelican.
 * Samuel (voiced by Marc Thompson) - A harbor seal.
 * Nanuq (also voiced by Kevin Michael Richardson) - A polar bear.
 * Ranger (also voiced by Phil Morris) - A bull caribou.
 * Prancer (voiced by Charlie Schlatter) - A pronghorn.
 * Shellbert (voiced by Phil LaMarr) - An eastern box turtle.
 * Frances (voiced by Cree Summer) - An American bullfrog.
 * Austin (also voiced by Jeff Bennett) - A green anole.
 * Gabe (also voiced by Tom Kenny) - A mountain goat.
 * Benson (also voiced by Daran Norris) - A bighorn ram.
 * Riley (voiced by Dee Bradley Baker) - A greater roadrunner.
 * Ace (voiced by Kevin Schon) - A nine-banded armadillo.
 * Gizo (voiced by Carlos Alazraqui) - A southern grasshopper mouse.
 * Chace (voiced by Jeffrey Garcia) - A chihuahua.
 * Betsey (voiced by Kimberly Brooks) - An English bulldog who is Chace's wife.
 * Cassie (voiced by Laraine Newman) - An American copperhead.
 * Bella (voiced by Janice Kawaye) - A little brown bat.
 * Queenie (voiced by Susanne Blakeslee) - A queen western honeybee.
 * Madina (also voiced by Candi Milo) - A monarch butterfly.
 * Boxing Joe (also voiced by Jeff Bennett) - A red kangaroo.
 * Dulari (also voiced by Grey DeLisle) - A Bengal tigress.
 * Twiga (also voiced by Tara Strong) - A reticulated giraffe.
 * Carl (also voiced by Dana Snyder) - A capybara.
 * Patricio (also voiced by Tom Kenny) - A blue-and-gold macaw.
 * Emperor Everett (voiced by Ian James Corlett) - An emperor penguin.
 * Empress Pheba (voiced by Wanda Sykes) - An emperor penguin.
 * Addie (voiced by Joanne Spracklen) - An Adelie penguin who is Emperor Everett's royal announcer.
 * Royal Kids (all voiced by Liliana Mumy and Elizabeth Daily) - An emperor penguin chick, a macaroni penguin chick and a gentoo penguin chick.
 * Oki (also voiced by Jennifer Hale) - A killer whale.
 * Williemae (voiced by Deedee Magno Hall) - A whooping crane pop-star.
 * Maurice (also voiced by Phil LaMarr) - An American mastodon.

Antagonists

 * Mister Bobtail (voiced by Mark Oliver) - A bobcat who is the forest's most evil mastermind.
 * Martin (voiced by Keith Ferguson) - An American marten who is Mister Bobtail's henchman.
 * Harry (voiced by Mike Pollock) - A red-tailed hawk who is Bullet's archenemy.
 * Princess Morbucks (also voiced by Jennifer Hale) - The only primary villian returning from the original series.
 * Grizz (voiced by Jim Cummings) - A grizzly bear.
 * Catherine (also voiced by Grey DeLisle) - A cougar.
 * Nova (voiced by Mindy Sterling) - A great horned owl.
 * Old Al (voiced by Fred Tatasciore) - An American alligator.
 * Randall (voiced by Maurice LaMarche) - A North American raccoon who is the leader of his raccoon gaze.
 * Cain (voiced by Stephen Root) - A coyote.
 * Blaze (voiced by Max Mittelman) - An eastern grey squirrel who is the Rowdyruff equivalent to Bullet, and he has superpowers like she does.
 * Freddie (voiced by Mark Hamill) - A red fox who is the most popular fox in the forest and being Reynard's rival.
 * Greg (also voiced by Jeff Bennett) - A golden eagle.
 * Helen (also voiced by Laura Bailey) - A northern harrier.
 * Devin (voiced by Jeff Bergman) - A northern mockingbird.
 * Hunk Hog (also voiced by Kevin Michael Richardson) - A wild boar.
 * Ratty (voiced by Doug Lawrence) - A brown rat.
 * Sia (also voiced by Susanne Blakeslee) - A Siamese cat.
 * Samir (also voiced by Carlos Alazraqui) - A star-nosed mole.
 * Silvia (voiced by Kathleen Barr) - A loggerhead shrike.
 * Willie (also voiced by Tom Kenny) - A least weasel.
 * Blackfoot (voiced by Rob Paulsen) - A black-footed ferret.
 * Buzzy Buzzard (voiced by Daryl Sabara) - A turkey vulture.
 * Beachmaster Ernest (also voiced by John DiMaggio) - A bull northern elephant seal.
 * Stella (also voiced by Grey DeLisle) - A northern short-tailed shrew.
 * Monty (voiced by Mark Whitten) - A black-billed magpie.
 * Ozzie (voiced by Eddie Deezen) - A Virginia opossum con-artist.
 * Waldo (voiced by Clancy Brown) - A Pacific walrus.
 * Vera (also voiced by Candi Milo) - A timber rattlesnake.
 * Raffee (also voiced by Daran Norris) - A western diamondback rattlesnake.
 * Saar (voiced by Jenny Slate) - A southern black widow.
 * General Aileen (voiced by Esme Bianco) - A red fire ant.
 * Pinky (also voiced by Jeff Bennett) - An alligator snapping turtle.
 * Monstruo (voiced by Jill Talley) - A Gila monster.
 * Drago (voiced by David Kaye) - A Nile monitor who has escaped from the pet store in Townsville.
 * Diablo (voiced by James Woods) - A Burmese python.
 * Gulo (voiced by Alan Tudyk) - A wolverine.

Trivia

 * Only seven characters return from the original series, as well as Dexter and Dee Dee from Dexter's Laboratory, as well as Beau from "Beau Tie". But this time, Bullet is the main character, while the girls became supporting characters.