The Powerpuff Girls of Townsville

 is an American action-adventure-thriller superhero fanfiction series based on  by Craig McCracken, being written by TBD aka TBD and published since November 18th, 2019.

Synopsis
Three college students finally learn that they were created by their father to become the ultimate heroes as they have to use their abilities to protect Townsville from various menaces who want to cause darkness.

Main

 * Blossom Utonium - one of Utonium's daughters who is extremely smart but is also secretly a lesbian as, when she discovers her powers, she learns that she is tuned to the fire element as she can fire lasers out of her eyes.
 * Bubbles Utonium - one of Utonium's daughters who is both kind and boy-obsessed as she learns that she is tuned to water as it gives her both agile reflexes and temporary healing abilities.
 * Buttercup Utonium - one of Utonium's daughters who is extremely reckless and she doesn't really think as she learns she is tuned to the Earth element as her strength is multiplied.

Supporting

 * Prof. Thomas Utonium - the cynical and calculating but deeply caring father of the Girls who hardly lets his emotions take over him but wants to make sure his daughters live.
 * Jen Utonium (née Keane) - the Girls' caring stepmom and former grade school teacher who cares about them dearly as she is the voice of reason behind Utonium.
 * Mayor Sara Bellum - the recently instated mayor of Townsville who is heavily booksmart as she wants to make sure Townsville is safe as she considers the Girls to be true heroes.
 * Robin Snyder - the Girls' extremely peppy best friend who keeps a smile on her face at all times and is aware of their heroics.

Antagonists

 * Dr. Manfred Johann/Mojo Jojo - Utonium's former partner who attempted to steal both his research and his pet monkey JoJo, as an accident fuses Johann and Jojo, birthing Mojo Jojo who wants to both rule Townsville and become a human again.
 * Adam Kadmon/Him - the banished supreme man who has been twisted into an extremely sadistic demon who wants to bring the end of the world so he can create it again.
 * Princess Morbucks - the heiress of Morbucks Industries who is obsessed with outsmarting the Powerpuff Girls as she has an equal yet creepy romantic obsession with Blossom.
 * Fuzzy Lumpkins - a mutant designed by Mojo to become the perfect man as it failed miserably as Fuzzy has grown bitter of humanity and wants to destroy it.
 * The Gangreen Gang, consisting of:
 * Ace Copular - the rebellious and charismatic leader of the street gang known as the Gangreen Gang who has a moral code which is "do crimes only when it destroys the reputation of the Man".
 * Sedusa - a hairstylist who had made dealings with the mob as she soon gets exposed to Chemical X, allowing her to control her hair as she wants to both murder the mob that transformed her and remove her condition.
 * Bossman, Slim and Junior/The Amoeba Boys - three Sicilian mobsters who mutate into living germs as they are now unable to be harmed.

Issues

 * 1) Sugar, Spice and Everything Nice - Three normal teenagers learn that they are actually superhuman experiments as they are forced to fight a face from their father's past.
 * 2) What's Up With Blossom - Blossom has been acting weird with the leader of the anarchist gang, the Gangreen Gang, as both Bubbles and Buttercup assume she is brainwashed by them. They soon learn that this isn't the case and it is actually love.
 * 3) The Freak - Mojo Jojo reluctantly forms an alliance with the Powerpuff Girls when his former creation, Fuzzy Lumpkins, has returned to kill him.
 * 4) Vengeance! - Mobsters have been getting slaughtered as the Girls investigate and discover a brutal self-claimed vigilante calling herself Sedusa.
 * 5) The Possession - Bubbles has been acting more deranged than usual as the girls learn that she is possessed by a demon that calls himself Him as they have to remove him from her body.
 * 6) The Cyberpuff Girls - Three robotic clones of the Powerpuff Girls have been solving crimes way faster than the actual girls as soon they learn who is responsible for this: the psychotic millionaire Princess Morbucks.
 * 7) You Talking To Me? - Three Sicilian mobsters mutate into living germs as they plan for the ultimate heist due to them being unable to be harmed. As a result, the Girls need to figure out how to beat villains they can't fight.
 * 8) Workout of Our Lives - Buttercup signs up for an intensive workout regimen as soon the other Girls learn that a new villain has taken control of the workout and plans to work Buttercup to death.
 * 9) At the Beach - The Powerpuff Girls go to the beach as things get terrible when Fuzzy Lumpkins has arrived to destroy everyone at the beach.
 * 10) Nightmare in Townsville - Him has returned and placed Townsville in a lucid nightmare-like state as the Girls have to survive the nightmares in order to stop Him.
 * 11) Sedusa's Return - Sedusa has returned and has started strangling scientists with her hair as the Girls have to stop her.
 * 12) Brains and Brawn - Mojo Jojo realizes that despite his intelligence, he doesn't have the strength to do it, so he creates three male dopplegangers of the Girls who now want to murder their female counterparts.
 * TBD
 * TBD

Differences

 * Townsville is a massive city.
 * The main trio, as well as Robin and Morbucks, is in their twenties.
 * Blossom is a lesbian while TBD.
 * Professor Utonium and Ms. Keane are married.
 * Ms. Bellum is the Mayor of Townsville and her face is visible.
 * Mojo is initially a human before mutating into an ape.
 * [Him]
 * The Gangreen Gang are an anarchist gang with Ace being a woman.
 * Sedusa is more sympathetic.
 * TBD

Easter eggs

 * Blossom has a slightly pornographic poster of the Hex Girls.
 * One of Utonium's old partners was Max Tennyson.
 * Blossom admitted she once crushed on Frankie Foster.
 * The Girls once fought Knightbrace which was shown on the news.
 * [Bubbles or Buttercup] owns a TuneSquad outfit signed by [Michael Jordan, Bugs Bunny, Daffy Duck or Lola Bunny].