City of Mayhem

City of Mayhem is an American animated comedy television series created by Sam Register. It was produced at Warner Bros. Animation, premiered on Cartoon Network on September 1, 2022, and ended on May 4, 2023.

Synopsis
In a world where humans, animals, food, inanimate objects, and creatures live together, a 15-year-old boy named Tyler Henderson, his brothers, cousin, and friends go through wacky shenanigans in the fictional city of Mayhem City, Massachusetts.

The Hendersons

 * Tyler Henderson, a self-concerned 15-year-old boy. He likes skateboarding and pizza.


 * Henry Henderson, a rock music loving 14-year-old boy and the brother of Tyler. He likes rock music, Home Alone, and slushies.


 * Travis Henderson, a quiet 13-year-old boy and the brother of Tyler and Henry. He likes Zootopia, WALL-E, and donuts. His eyes are covered by his hair.


 * Nathan Henderson, a secretive 13-year-old boy and the cousin of the brothers. He likes The Big Bang Theory and Cheetos.

Tyler's friends

 * Emma Morrison, a kind 13-year-old chocolate bar and the friend of Tyler. She likes Monopoly and sandwiches.


 * Keith Peterson, a curious 11-year-old cat and the friend of Tyler and Emma. He likes Oreos.

The Hendersons

 * Emily Henderson, a funny 15-year-old girl and the sister of the brothers. She likes CatDog and The Angry Beavers.


 * Lisa Henderson, a pop music loving 14-year-old girl and the sister of Emily and the brothers. She likes pop music.


 * Tina Henderson, a nerdy 13-year-old girl and the sister of Emily, Lisa, and the brothers. She likes math and science.


 * Sally Henderson, a sophisticated 13-year-old girl, the cousin of the sisters and brothers, and the sister of Nathan. She likes puffins.


 * Bia Henderson, a childish 10-year-old girl and the youngest sister of the sisters and brothers. She likes onion rings.


 * Greg Henderson, a mischievous 9-year-old boy and the youngest brother of Bia, the sisters, and the brothers. He likes Minecraft.


 * Bob Henderson, a wholesome 40-year-old man and the father of the sisters and brothers. He likes bowling.


 * Brandy Henderson, a charming 38-year-old woman, the wife of Bob, and the mother of the sisters and brothers. She likes pudding.


 * Jake, a toco toucan, the Hendersons’ family pet, and Henry’s pet toucan. He likes mangos.


 * Sophia, a black cat, the Hendersons’ other family pet, and Nathan’s pet cat. She likes peanut butter.

Mayhem City High

 * Daniel Duck, a smart 14-year-old duck and the classmate of Tyler. He likes calculus.


 * Liam Anderson, a sleepy 15-year-old boy and the other classmate of Tyler. He likes beds.


 * Leo Danielson, a sneaky 14-year-old boy and the other classmate of Tyler. He likes Over the Hedge. He wears a mask.


 * Ella Danielson, an emo 14-year-old girl, the other classmate of Tyler, and the sister of Leo. She likes goth music. Her eyes are covered by her hair.


 * Skylar Reat, a hyperactive 13-year-old toaster and the other classmate of Tyler. He likes cookies.


 * Bree Anderson, a perky 13-year-old girl, the other classmate of Tyler, and the sister of Liam. She likes burned toast.


 * Mr. John Selleck, a strong-minded 42-year-old man and the teacher of the students. He likes teaching.

Mayhem City residents

 * Todd Lopez, a neighbor of the Hendersons and a father.


 * Rachel Lopez, a wife of Todd.


 * Sam Lopez, a daughter of Todd and Rachel.


 * Kevin Lopez, a little brother of Sam and son of Todd and Rachel.


 * Shawn Lopez, a big brother of Kevin and Sam and son of Todd and Rachel.


 * Jasper Madison, a teenage boy who talks about the Hendersons' antics.


 * Felix Keller, a friend of Jasper.

Mayhem City professions

 * Brock Book, a teenage boy who works at a bakery called “The Happy-Go-Lucky Bakery”.


 * Mayor Arthur Bryce, the mayor of Mayhem City.

Cast

 * Eric Bauza as Tyler & Mr. Selleck


 * Mitchel Musso as Henry & Daniel


 * Seth Green as Travis & Bob


 * James Arnold Taylor as Nathan, Liam & Skylar


 * Jessica DiCicco as Emma, Tina & Brandy


 * Iain Armitage as Keith & Greg


 * Grey Griffin as Emily, Bree & Ella


 * Tara Strong as Lisa, Bia & Sally


 * Kevin McDonald as Leo

Setting
The show takes place in the fictional city of Mayhem City in Massachusetts. Mayhem City is a city where everything and everybody are crazy, weird, and odd. All the people, animals, vehicles (like cars, boats, and trains), food, and buildings have different colors, designs, personalities, and sizes. The residents of the city have different character designs (some of them are stick figures, some are elements, and some are plain humans).