Supremely Irresponsible

Supremely Irresponsible is an American action-adventure comic book limited series published by Marvel Comics which follows the characters Supreme Spider and Irresponsible Spider-Man while they fight against the villainous Runaway Son.

Main

 * Mary Jane Watson/The Supreme Spider - a very kind-hearted teenage girl who has an anti-heroic split personality.
 * Peter Parker (Earth-29815)/Spider-Man - a self-proclaimed rebel without a cause with a strict moral code.

Supporting

 * Peter Parker (Earth-47599) - MJ's kind boyfriend who is unaware of her dual identity and one of the only people she won't hurt.
 * Gwendolyne "Gwen" Stacy (Earth-47599) - MJ's best friend who dislikes the Supreme Spider and wants to figure out who she is.
 * Harold "Harry" Osborn (Earth-47599) - Peter's best friend who is the son of the underground mob boss Kingpin.
 * Gwendolyne "Gwen" Stacy (Earth-29815) - Irresponsible Peter's best friend who is another delinquent.
 * Harold "Harry" Osborn (Earth-29815) - Peter's best friend who is his only non-delinquent friend.
 * Eugene "Flash" Thompson (Earth-29815) - Peter's main rival at school.

Antagonists

 * Peter Parker (Earth-5892)/The Runaway Son - a spider who hates Spider-Men.
 * Overdrive - a mysterious masked assassin who is able to turn any form of technology into something better.
 * Sally Avril/Shocker - a teenage delinquent who stole a pair of powerful gauntlets.
 * Jefferson Davis/Tombstone - a former cop who is turned into an indestructible mob enforcer.
 * Elektra Natchios - a woman trained in several martial arts who wants to die in a fight with Spider-Man.
 * Raniero "Blackie" Drago/Vulture - a terrorist in a suit that allows him to fly.
 * Maxwell "Max" Dillon/Electro - an electrician who was mutated into an electrokinetic criminal.

Issues

 * 1) /The Good, The Bad, and the Ugly/ - Peter and Mary Jane meet each other.