Deathspider / Markus Katrino

Deathspider/Markus Katrino is the title character and protagonist of the American animated television series of the same name. Deathspider is known under the editorial names Arachnid with a Mouth and Regenerating Degenerate thanks to his talkativity and constant breaking of the fourth wall for comedic effect.

The character's popularity has seen him featured in numerous forms of other media. In television, he is voiced by Seth MacFarlane, who created the series.

Personality
Deathspider is aware that he is a fictional character. He commonly breaks the fourth wall, which is done by few other characters in the Deathspider universe and this is used to humorous effect. Deathspider is depicted as having an accelerated healing factor, which not only prevents him from being permanently injured through enhanced cell regeneration throughout his body, but also causes psychosis and mental instability, as his neurons are also affected by the accelerated regeneration. It is thought that while his psychoses are a handicap, they are also one of his assets as they make him an extremely unpredictable opponent. Drone Soldier, who has photo-reflexive memory which allows him to copy anyone's fighting skills by observation, was unable to defeat Deathspider due to his chaotic and improvised fighting style.

The character, known for his talkative nature, has been nicknamed the "Arachnid with a Mouth".

Deathspider has sometimes been portrayed to have a strong sense of core morality.

Deathspider is talkative and mentally unstable, having a humorous and goofy nature.

Powers and abilities
Deathspider's primary power is an accelerated healing factor,( It gives him the ability to not die) depicted by various writers at differing levels of efficiency. Artificially endowed by FoxCorp's genetics program, this enables him to regenerate any destroyed tissue at a superhuman rate, as well as making him immune to diseases. Deathspider's healing factor is strong enough that he has previously survived complete incineration and decapitation more than once. Although his head normally has to be reunited with his body to heal the wound, he was able to regrow his head after having it pulverized by a rift reaper.

Deathspider's brain cells are similarly affected, with dying neurons being rejuvenated at a super accelerated rate. This allows Deathspider to recover from any head wounds, and it renders him nearly invulnerable to psychic and telepathic powers, although this ability is inconsistent. It has been revealed that at the time that his healing ability was given to him, Deathspider suffered from some form of cancer. After the healing factor was given to him, it made his normal cells as well as his cancerous cells unable to die, turning him into a human-size spider.

Deathspider's body is highly resistant to most drugs and toxins, due to his enhanced cell regeneration. For example, it is extremely difficult for him to become intoxicated. He can be affected by certain drugs such as tranquilizers, if he is exposed to a large enough dosage.

Deathspider is effectively immortal, although he has died several times. He is still alive 800 years in the future when the new Web-Force encounters him. In addition, Zentrous once declared that Deathspider should "consider yourself cursed ... with life!" out of jealousy over Deathspider's status as an undying leader.

Deathspider is a highly trained assassin and mercenary, adept in multiple forms of martial arts, and an expert swordsman and marksman. Although in earlier years he was originally portrayed as having superhuman strength, he is no longer depicted as having this ability.

Over the years, Deathspider has owned a number of personal teleportation devices. Also, during Deathspider's first ongoing comic, he possesses a device which projected holographic disguises, allowing him to go undercover or conceal his appearance. He also has a magic satchel containing all of his unlimited weaponry and ammo. Deathspider is multilingual, with the ability to speak fluently in German, Spanish, ASL and Japanese, in addition to his native English.

Deathspider also has has an extraordinary sense of danger. It tingles at the back of the skull when he can sense danger around himself.

Since Deathspider is aware that he is a fictional character, he uses this knowledge to his advantage to deal with opponents or gain knowledge to which he should not normally have access, such as "reading" past issues of his and others' comics. Deathspider even knows he has a Wikipedia article and hopes his fans keep his page updated.

Television
In his show he is voiced by co-creator Seth MacFarlane.

Video games
an action game based on the character, was developed by High Moon Studios and published by Activision in 2023, with Seth MacFarlane reprising his role.

Trivia

 * Deathspider was inspired by Deadpool and Spider-Man