The Ups & Downs of Dating A Supervillain

The Ups & Downs of Dating A Supervillain is an American adult animated superhero sitcom developed and created by Seth Carter for Cartoon Network's Adult Swim block, premiering on the network on June 15, 2021. The series follows the self-proclaimed supervillain Tina McCree, AKA Doctor Toxin, who has recently begun dating her new boyfriend Max Fischer, with them attempting to have a functioning relationship despite Tina's career choice often bringing forth unwanted excitement. The series has been praised for its animation and writing, most notably when it comes to its two protagonists.

Premise
Set in a world populated by superheroes and villains alike, the series follows the supervillain/mad scientist Tina McCree/Doctor Toxin, who has dedicated her life to the complete and total conquest of the world, although she seems to have lost some of her credibility in more recent years. Recently, she has met and begun dating IT worker Max Fischer, who lives a much more normal life in comparison. The two try their best to have a normal and healthy relationship in spite of their everyday lives often mixing together with Tina's supervillain life.

Main

 * Aubrey Plaza as Tina McCree/Doctor Toxin, one of the series' two main characters and the one who gets the most focus between the two. She is an eccentric, narcissist, and megalomaniac who has dedicated her life to conquering the world using her intellect and mastery in all forms of science and medicine. She also suffers from paranoid tendencies and is stated as having both a superiority and inferiority complex. Her backstory is frequently explored throughout the series, showing off what caused her unique mindset. She is heavily inspired by and even sometimes pastiches aspects of the Silver Age rendition of Lex Luthor.
 * Nicholas Hoult as Max Fischer, the other of the series' main characters. He is Tina's boyfriend (supposedly her first ever) and works for the IT department of a company called BlazeCorp. He seems to be the overall caretaker of the house, doing most of the cooking and cleaning due to Tina lacking the know-how herself. He is also characterized as having an obsession with social media, often being seen scrolling on his phone or taking/uploading pictures to it, and a recurring gag is that he is completely desensitized to most of Tina's more strange and amoral actions.

Recurring

 * TBA as Randall/Major Venus, Doctor Toxin's archenemy who, when it comes to his role in the story, is a pastiche of the character Superman, though he shares few powers with him. He has various psychic abilities including, but not limited to, telekinesis, telepathy, technopathy, and more. He is also the most popular superhero in the world, though later events in the series reveal he is unfulfilled with his career and is generally unhappy with his life.
 * Keith David as Knuckle Duster, the overall main antagonist of the series, though his on-screen appearances throughout it are brief. He is an outcast from the superhero community with a sense of justice that has overtaken him and caused him to go on a brutal murder spree against supervillains, who he beats to death with his namesake weapons.