Zippy: The Movie

Zippy: The Movie is a 2026 American animated adventure comedy film based on the Disney Channel animated television series, Zippy and produced by Walt Disney Animation Studios and released by Walt Disney Pictures. It is the 63rd Disney animated feature film. Written and directed by series creators Brandon Greene and Kyla Greene, it features the series' regular voice cast with Will Ferrell, Alec Baldwin, Demi Lovato, Kristen Bell, Ed Sheeran, and Jane Lynch voicing new characters. It is the first film in the Zippy: The Movie film series. In this film, Zippy finds one of the five Star Crystals that when all are gathered together can grant one wish. But then What's-It's-Face gets it and uses it power to rule Ziptown and enslave everyone in it. With the help from two teenage girls named Vanessa (Lovato) and her friend Gabi (Bell), Zippy and his friends must travel all across Manhattan and London to find the other four Star Crystals and save the world from What's-It's-Face's rule.

Disney Animation accepted an offer for a film adaptation of Zippy from Brandon Greene in 2024. Brandon and Kyla assembled a team from the show's writing staff, including Cameron Perez, Dan Povenmire, Jeff "Swampy" Marsh, Alex Hirsch, Matt Braly, Bill Motz, and Bob Roth. The film was originally intended to serve as the series finale, but Disney ordered more episodes of the series as it had become increasingly profitable, so Kyla resigned as co-showrunner, with her brother would remain as showrunner.

Zippy: The Movie was released theatrically in the United States on June 19, 2026 and received mostly positive reviews from critics. It was also a box office success, earning over $480.7 million worldwide against its $103 million budget. At the 99th Academy Awards, the film received two nominations for Best Animated Feature and Best Original Song (Ed Sheeran's "Change The World"). Two standalone sequels have been released: Zippy: The Movie 2: Family Road Zip (2037) and Zippy: The Movie 3: A Zip Through the Internet (2043).

Plot
One night, five shining objects in the sky fall all across the world. One falls near a cave in Ziptown. The next day after school, Zippy and Wet Willy try to blow the biggest bubble that could last. Zippy blows a bubble so big that it engulfs them both and carries them into a nearby cave. The bubble suddenly pops as it makes an impact with the shining object that fell from the sky last night.

Eager to discover what exactly it is, they decide to take it to the Burger Shack at the Zip Central Mall, where they explain to their friends about what they found. At first, Zack thinks that Zippy and Willy were planning to steal the Star Crystal, which is housed in the Shack, but upon attempting to return it to its spot, he realizes that what they had was, in fact, another Star Crystal which all crystals put together can grant one wish. Suddenly, Shadow, Hazel, Von Papperoth, and Freddy Bear in a ice cream truck drove by, sending out invitations to a feast in What's-It's-Face's Funhouse to apologize for his wicked behavior. Meanwhile, the twins Jack and Mack get invitations as well and they decide to head to What's-It's-Face's Dinner Party. Meanwhile, Flambo enters his dog house and Bubbles reveals that Flambo has an auto-scan replication device which he uses to scan and replicate all of Whiskers' evil inventions and that he recuited detective Chihuahua Pepe on their mission. Flambo and Jane leave the doghouse in a hovercraft to stop Dr. Whiskers.

Curious and spectacle, the crew sets off for the funhouse, but upon their arrival, they find it was a trick as What's-It's-Face and his henchmen trap Zippy and his friends in a cage when they enter. With the group trapped, What's-It's-Face takes the crystal and he and the others head to the Burger Shack to steal the other one. Displeased by the outcome, the gang escaped and head off to the mall. Open their arrival, What's-It's-Face and his attacks the Burger Shack in an attempt to steal the other Star Crystal. After a battle involving giant foods and condiments, What-It's-Face attempts to steal the crystal, but he and Zippy tries to stop him. While Zippy and What's-It's-Face fight over the Star Crystal, Shadow steals the Zip Burger secret formula and sells it to the Sugar Rush Candy Company in Manhattan.

Slugger, roller skating out of control, accidentally swipes the Star Crystal leading to a chase around the mall and Ziptown. The crystal falls into the sewer. Without the secret formula, Zip Burgers cannot be made, causing customers to become ravenous. What's-It's-Face, realizing that the Star Crystals could grant a wish once put together decides to find them. Zippy creates a giant soap bubble, in which he flies away. Ziptown is immediately reduced to a wasteland due to the absence of the much-relied-on Zip Burger. Flambo and Jane crash into Dr. Whiskers' lab but are trapped. While Floppy and Baby Bert leave the lair assist Whiskers in repairing his new invention the Power-Consuming Staff, Buddy sees them and helps them to escape and head to Manhattan.

Zippy and Wet Willy propose teaming up with their friends to find the the Star Crystals. When they get chased by an angry mob, they run away and decide to leave Ziptown until it's back to normal. That night, they camp in the middle of nowhere and lament that if they don't save Ziptown, they will never see any of their friends or do any of the fun things they used to do again, causing Zippy and Willy to be sad and miss their old lives. However, they find an old plane and use it to fly around the world to find the Star Crystals. What's-It's-Face finds out about this and rides his helicopter after the duo. What's-It's-Face uses Bomb Charges to take down the plane and the Zippy and Willy fall down the river and into the sewers. This leaves What's-It's-Face and his henchmen to look for the three other shining objects, the Star Crystals, in peace.

After going into the sewers and enter Manhattan, New York City, they decide to head around the town to find the other Star Crystals and settle the score with What's-It's-Face. Meanwhile, What's-It's-Face meets Dr. Whiskers and he gives him the staff to use the Star Crystal's power. They invite many of Zippy's foes and persuades them to get the other Star Crystals, destroy Zippy, and conquer Ziptown.

While exploring around the city, they stop at a college called "Zipruch University" where they run into Principal Wiggles and introduces them to the CEO of Sugar Rush Candy Company, Kurt T. Clampitt and he and his loyal butler Edmonton take them a tour around the campus, while also revealing that he was Mr. Baxworth and What's-It'-Face's old college roommate. Zippy and Wet Willy meet two college students named Vanessa Duncan and Gabi Buyer and they followed them to their class. Zippy tells them that they came to Manhattan to find the Star Crystals to save Ziptown and they need their help. Vanessa isn't having two zip kids following her around, but Gabi wants Zippy and Willy to stay since Vanessa has the Star Crystal. Vanessa agrees to this and she and Gabi take Zippy and Wet Willy to their room to see Flambo and Jane with Vanessa's pet Chihuahua Pepe is.

Back in Ziptown, Ceela, Jenny, Zoomie, Jolly, and Pinky find out that Zippy and Wet Willy are missing and convinces everyone in town to form a search party for the two. Ceela and Jenny have them search in dangerous places. After hours of searching with no success, they all want a break, but Pinky does not relent and demands that no one leaves until they find Zippy and Willy. What's-It's-Face and other villains show up and attack Ziptown. They storm the mall and Burger Shack and trap Mr. Baxworth and Zack in a toilet, but Slugger, Franklin, and the Burger Shack employees stall them long enough for Ceela, Jenny, Zoomie, Jolly, Pinky, Billy, and Frankie to escape. The Lange Brothers accidentally reveals that Zippy and Wet Willy have gone to retrieve the Star Crystals. What's-It's-Face sends Shadow, Von, Teddy, Baby Bert, Floppy, Pastrilum, and Vandit to track them down. Billy, Frankie, their friends, and the Burger Shack employees are trapped in the kitchen while Ceela, Jenny, Zoomie, Jolly, and Pinky are thrown out of the city. They witness their beloved city of becoming worst and What's-It's-Face declares himself Emperor of Ziptown. Finding out that Zippy and Wet Willy are in Manhattan decide to go there.

The next day, Vanessa, and Gabi head to class, while Flambo, Jane, Pepe, and Buddy turn on the TV and Pepe's boss Agent 60 appears on screen. Agent 60 informs that someone is on the verge of searching for all the Star Crystals and might use them for something terrible. Jane gets the idea to team up with Zippy and his friends to stop this. Before leaving, Wet Willy defends a student named Damian from bullies and Zippy helps Vanessa with her relationship with her boyfriend, Brian Paul, an exchange student from London. Brian asked Vanessa if she and Gabi would like to go to his party and thanks to Zippy's encouragement, she accepts. After escaping some harmless stray dogs, Flambo, Jane, Pepe, and Buddy discovered a device that could find the Star Crystals. Baby Bert and Floppy find them and try to capture them, but Flambo, Jane, and Pepe defeated them, not before revealing that Dr. Whiskers has joined the villains. Flambo heads to Zippy and gives him the tracking device.

Meanwhile, the gang arrive at Manhattan and they split up to find Zippy and Wet Willy. Ceela and Jenny go to a direction and Zoomie, Jolly, and Pinky go in another direction. Zoomie, Jolly, and Pinky meet Brian and he let's them stay in his room for a while. Brian tells them that he has seen Zippy and Willy with Vanessa. But a series of mishaps of searching for Zippy and Willy have Zoomie and Jolly labelled quarter thieves/statue smashers, landing them in jail where they got along with the prisoners.

Back in Ziptown, Billy and Frankie escape the kitchen at the Burger Shack and go to confront What's-It's-Face. Before Billy can leave and alert Zippy, What's-It's-Face unleashes the two Star Crystals' powers on a mind-control device that Dr. Whiskers built to control the citizens of Ziptown and sends them after Billy and Frankie and throwing them in his dungeon along with Zack and Mr. Baxworth. Meanwhile, Zippy and Wet Willy go to the Sugar Rush Candy Company that now sells all new Sugar Burgers and Clampitt gives them a machine to find a Star Crystal in an Amusement Park called "Fun City". Flambo and Jane find Ceela and Jenny and leads them to Zippy and Wet Willy.

Zippy and Willy use the device to track down the Star Crystals and one of them is at Fun City, run by Mr. Jeffrey. At the same time, Von, Shadow, Hazel, Freddy, and the other villains pursuit them. As night falls, they stop at a local diner. When Zippy asks about where the Star Crystals are, the pub-goers become hostile. The pair decide to leave, and a Native American zip person named Jim warns them to keep to the road, stay clear of the moors and beware of any place that might deceive them. Arriving at Fun City, they approach Jack and Mack, who both gotten lost on the way to What's-It's-Face's funhouse and they tell them that they should try the city's attractions. While on the attractions, the villains (as well as Edmonton) try to dispose of the pair, but all failed.

After a fun-filled night, Zippy and Willy discover a Star Crystal that Mr. Jeffrey has. Willy decides to "take him out" but Zippy gets another idea to sneak in and take the crystal. As they sneak in, they are reunited with Ceela and Jenny (as well as Flambo and Jane) who tell them that What's-It's-Face and their enemies have taken over and mind controlled everyone in Ziptown and that Zoomie and Jolly are in prison. Meanwhile, Pepe discovers that Mr. Jeffrey turns the kids into pigs for their misdeeds and sells them to slave labor in circuses or be killed for food in slaughterhouses. Zippy, Wet Willy, Ceela, Jenny, Flambo, and Jane witness a boy transforming into a pig, and with Pepe's help, the team along with Jack and Mack escape with the Star Crystal, though they have to abandon the kids in the clutches of Mr. Jeffrey (even if Zippy tries to call the police about the incident). Zippy asks Jack and Mack if they'd like to join them, but they decline saying that they recall the free food promised at What's-It's-Face's Funhouse, and eagerly head off towards the funhouse.

During Zoomie and Jolly's stay in jail as it supposedly comes to an end, the warden then approaches them and tells them that their stay has been extended an additional thirty days. Learning from another prisoner that they might be locked up forever, the group decides to break out of the prison when the prison guard's eyes are diverted. With the help of Pinky and Brian, as well as some of the other prisoners Zoomie and Jolly were hanging, they were successful in their attempt. They are soon reunited with Zippy, Wet Willy, Ceela, and Jenny and come across a house where they discover a set of handcuff and shackle keys. The entire police force then comes after them, until they are able to jump on a train, only to be met by the sheriff and his deputies. Jane, however, wrecks the sheriff's car and demands he leave.

Later, Vanessa and Gabi dress up and go to Brian's party and brings Pepe along. There, Vanessa and Gabi meet Zippy and Wet Willy's friends where they warn them about What's-It's-Face and that Manhattan will be next to be taken over if all Star Crystals are found. Vanessa discover that Brian habitually cheats on her rival and bully Elizabeth due to love for Vanessa and how she is a good person to Zippy and how she loves Pepe. Distraught, Vanessa leaves the party and Zippy follows. Zippy tells Vanessa everything about what happened yesterday at Fun City that Clampitt sent them and that they have the Star Crystal, which makes Vanessa grow suspicious about Clampitt.

Vanessa and Gabi go to the library to research the Star Crystals and Flambo and Pepe sneak in; there they showed the girls what they discovered and learned the truth about Clampitt. When Clampitt was a 8-year-old boy, he was living with his father, Sir Vernon Clampitt, who is the original owner of Sugar Rush Candy Company, When Kurt turned 18, he was sent to college by where he met a young Mr. Baxworth and Larry Zippington (What's-It's-Face) and became the perfect team. Kurt's father says not to trust a Zip person saying they can ruin him, which did happen when Larry and Baxworth nearly destroyed the Sugar Rush Candy Company and his father scolds him for it. 12 years later, his father was killed in an accident caused by a crazy driving zip person and Kurt became bitter and paranoid, vowing to get revenge on all other zip people, and eventually becomes the 15th richest man in Manhattan. He also plans to create a plan to destroy all Zip people in order to take over the world. Pepe makes the connection if he gets all five Star Crystals, he'll use it to wish to destroy all zip people kind.

Meanwhile, Von, Shadow, Freddy, and the villains catch up to Zippy and his friends. Zippy avoids capture, and Shadow reveals What's-It's-Face's takeover of Ziptown and that Manhattan is next. Zippy and Wet Willy arrive back at the Sugar Rush Candy Company, but before they can give Clampitt the Star Crystal, Vanessa and Gabi confront them, revealing his true nature and that he has the Zip Burger secret formula, artificially enhanced with Triampathol, an illegal food chemical. Clampitt tries to persuade Vanessa into giving him the two Star Crystals (the other Zippy has and the other around Vanessa's neck) in exchange for the secret formula. Vanessa refuses and he sends his Sugar-Bots after them to take the Star Crystals by force. Jenny sees them and with her help, Zippy, Wet Willy, Vanessa, and Gabi, taking both the crystals and secret formula with them. As Clampitt gets even more fustrated with Zippy and Vanessa, Edmonton comes in to bring him his coffee and informs him that someone at the door who wants to see him. It was What's-It's-Face. Clampitt still angry at what he did, tries to throw him out with his Sugar-Bots. But What's-It's-Face persuades him to destroy multiverses with zip people in it, which interests Clampitt greatly. On What's-It's-Face's ship dungeon, Mr. Baxworth's wallet begins going crazy over all of the loose change he isn't earning, so Mr. Baxworth lets the wallet go so it can get to the money, only to be picked up by Damian.

When Zippy and friends are at Zipruch University, What's-It's-Face unleashes the mind-controlled townspeople to ransack the campus and lynch them. Clampitt uses his robots and Dr. Whiskers mind-control machine to mind control the people in Manhattan after the gang. Zippy, their friends, Vanessa, Gabi, and Pepe escape through a sinkhole that Jane hid using a sandbox, which destroys the campus soon after. The team escape with Brian and flee to London using a blimp that he won in a basketball game.

When they arrived in London, they head to Brian's old apartment where they have to find a way to stop What's-It's-Face and the villains. Vanessa explains to Brian about the situation and how she and Gabi met Zippy and Wet Willy. At the London Zoo, when they see What's-It's-Face's ship, Flambo, Jane, and Pepe decide to investigate inside. While trying to retrieve the scepter, Flambo and Pepe are captured by Dr. Whiskers and his henchmen and sends them both to the pound. In Piccadilly Circus, Vanessa calls her parents and tells her she's in London. Zippy, Wet Willy, Ceela, and Jenny suddenly see Agent 60 outside of a movie theatre. Inside, they tell Agent 60 that Camplitt and What's-It's-Face are working together to find the Star Crystals to destroy all zip people. Agent 60 tells them that this is there biggest mission yet to save the world since Flambo, Jane, and Pepe have the same mission. Suddenly, Jane shows up to tell Zippy that Flambo and Pepe were captured. Ceela discovers that Vanessa lost the Star Crystal necklace during the scuffle, and Clampitt finds it and sends it to What's-It's-Face, but let's him have it. With three Star Crystals, he chases Zippy and his friends off as he transforms London and Clampitt uses his a modified version of Dr. Whiskers' mind-control device to mind-control everyone (including Brian) in it. Zippy sees Mr. Red and Zack and frees them, just as Clampitt discovers them, ignores them about when the customers are going to find out about his alliance with What's-It's-Face, and calls an acquaintance named Wade, who has Vanessa and Gabi committed to an asylum called Demented Hills so that they cannot tell anybody else about this and Zippy and his friends to What's-It's-Face's fun dungeon where Billy, Frankie, and the rest of their friends are.

What's-It's-Face hosts a mock game show in the funhouse. Zippy and his friends are promptly sucked in a pinball machine by What's-It's-Face and Dr. Whiskers, the latter using it to mess with them. During this, What's-It's-Face warning against escaping at the risk of agitating the flint; everyone in the Z-Team save for Zippy. When What's-It's-Face threatens to ignite the gasoline, Zippy escapes and triggers a blaze, but uses an explosive to blow its roof open, allowing water to rush in from above and douse the flames. He frees the others and head to find Flambo and Pepe. Meanwhile, Jane rescues both Flambo and Pepe by breaking the animals out of the London Zoo and later, they find their friends.

Mr. Red confronts What's-It's-Face and Camplitt and demands him to hand over the three Star Crystals. However, What's-It's-Face manages to use the scepter to control Mr. Baxworth, and tells him to attack Zippy and his friends. When he has them cornered, Ceela throws jelly that she made earlier in the film at him, causing Mr. Baxworth to come to his senses. Pepe rescues Vanessa and Gabi, but Clampitt and a mind controlled Brian shows up and Clampitt orders him to attack them. Just as their cornered, Zippy throws Ceela's jelly at Brian and he turns normal again, embracing Vanessa. Later, Wet Willy uses a hose to blasts jelly on some of their brainwashed friends, as well as the Burger Shack employees.

Seeing that Ceela's jelly is the antidote, Zippy, his friends, and the Burger Shack employees arm themselves with jelly guns and Zippy declares war. Zippy, his friends, Vanessa, Gabi, Brian, Pepe, the employees, and the customers (along with Agent 60 and Bubbles) get their weapons and confront What's-It's-Face, Clampitt, the villains, and the mind controlled townspeople of Ziptown, Manhattan, and London. They start the war, and Zippy and his team use jelly guns to free the citizens and defeat Zippy's enemies. Zippy and What's-It's-Face fight through time and space while Pepe, with Vanessa's aid fights Camplitt on a rooftop where Pepe could destroy the mind control device. Camplitt creates a machine to delete zip people and pushes the lever on the machine further that starts causing the portals and the inhabitants to be erased from existence. Camplitt reveals that he has destroyed 20% of the multiverse and blackmails Pepe, Zippy, Vanessa, and the rest of the world into making him their new leader and buy his sugar rush candy company products or he will destroy them all if they don't. But Vanessa stubbornly refuses and Camplitt loses what's left of his sanity and pulls the lever all the way to delete the universes as he decides to kill both Vanessa and Pepe by using a claw to put them on his conveyor stamper.

However, his plan is thwarted, when Flambo knocks Dr. Whiskers into a release button that causes Vanessa and Pepe to be released and Pepe pushed the emergency button and gets the Star Crystal and destroys both the deletion machine and the mind control device, both freeing the entire townspeople and restoring the multiverse. Pepe launches a basket over Camplitt's shoulders, incapacitating him. Wet Willy accidentally knocks Triampathol into the meat grinder during the fight. During the battle between Zippy and What's-It's-Face, Zippy's friends come to his aid. Just when Zippy's spatula sword is knocked off, the gang eventually get the scepter and Zippy, using his magic skills and with help from Flambo and Wet Willy, destroys the scepter which frees the three Star Crystals. The tower then begins to collapse, as the burgers begin to explode due to the overuse of Triampathol (because when too much of the chemical is added, the food that is used for under a cooker might explode). This causes most of the villains to flee before What's-It's-Face is knocked off dangling helplessly on a helicopter as he laughed maniacally until he was was approached by Carl and his police team at gunpoint. Distraught, Damian shrieks out in fury and despair over his failure. Afterwards, Vanessa punches Camplitt in the face, knocking him off into an island in the London Zoo filled with seals near his destroyed machine, which falls on top of him and is arrested for his crimes. With What's-It's Face now powerless, he and the rest of the villains are also arrested. With their enemies defeated, Zippy and Vanessa form all five Star Crystals together and even if Zippy wants to wish for the new Ratman Lost Episode video tape (which he mentioned a promise to his friends earlier in the film), he wishes for everything to be restored to normal.

When Zippy made his wish, he and friends return to Ziptown. Vanessa comes over to Zippy's house to gives him the Ratman video tape and asks if she and Gabi can hang out with him and his friends. With the secret formula back, The Burger Shack then returns to business and the celebration is ready to begin. Meanwhile, What's-It's-Face, on the other hand, escaped from the police and was discovered by Mr. Baxworth and was frozen by Carl and escorted to a mental institution. Mr. Baxworth then holds the door open for Damian who turns out to be the same person who took his wallet and Mr. Baxworth goes after him. Zippy and his old and new friends all watch the Ratman lost episode.

Throughout the movie, The Narrator serves as hosts, and some of the characters interrupt the film at certain points. In a after-credits scene, Jack and Mack eat the entire feast by themselves, being quite satisfied.

Voice cast
See also: List of Zippy characters


 * Michaela Dietz as Zippy
 * Dante Basco as Wet Willy
 * Laura Marano as Ceela
 * Dove Cameron as Jenny
 * Ross Lynch as Zoomie
 * Calum Worthy as Jolly
 * Kari Wahlgren as Pinky
 * Mark Hamill as What's-It's-Face
 * Will Ferrell as Kurt T. Clampitt, a billionaire and corrupt CEO of Sugar Rush Candy Company who hates zip people and wants to rid the multiverse of them. He is the secondary antagonist of the film.
 * Alec Baldwin as Pepe, Vanessa's pet Chihuahua and Manhattan's greatest detective.
 * Demi Lovato as Vanessa Duncan, a teenage college student who is Gabi's best friend and Pepe's owner.
 * Everly Carganilla as Young Vanessa
 * Kristen Bell as Gabi Buyer, a teenage college student and Vanessa's best friend.
 * Miriam Spumpkin as Young Gabi
 * Ed Sheeran as Brian Paul, an popular exchange student from London and Vanessa's boyfriend.
 * Jane Lynch as Agent 60, a secret agent leader and Pepe's boss.
 * Jeremy Shada as Billy Peterson
 * Ashly Burch as Frankie McKean
 * Patton Oswalt as Flambo
 * Brenda Song as Jane
 * Jason Earles as Zack Hathaway
 * Clancy Brown as Mr. Baxworth
 * Dan Povenmire as Dr. Whiskers
 * Alan Tudyk as:
 * Edmonton, Kurt's butler and right-hand man.
 * Mr. Jeffrey, the owner and operator of Fun City, where unruly boys are turned into donkeys and sold.
 * Tudyk also voices Von Papperoth, Steve McKean, Vandit, Prisoner #2, Alien #1, and Stray dog #1
 * Kerri Kenney-Silver as Flo
 * Brian Hull as Greg, Frank (The Wilhelm Scream Guy), Sugar-Bots, General Keegan, Three-Eyed What, Congress, Prisoner #1, Alien leader, Pub-goer #3, Stray dog #2
 * Jessica DiCicco as Zalow
 * Justin Felbinger as Zane
 * China Anne McClain as Tiff Malcolm
 * Anna Akana as Mandy Kwan
 * Dylan Sprouse and Cole Sprouse as Jack and Mack
 * Jason Marsden as Slugger, Blu-Jay, Student #3
 * Bradley Steven Perry as Nick Marshall
 * Lara Jill Miller as Allie Jones
 * Kelly Osbourne as Hazel
 * Gilbert Gottfried as Shadow
 * Brad Garrett as Freddy Bear
 * Bob Odenkirk as Principal Wiggles, the principal of Zipruch University.
 * Josh Gad as Damian, a nerdy college student who gets bullied for being "just off the boat".
 * Stephanie Beatriz as Elizabeth, Vanessa's bully and rival for Brian's affection.
 * Matt L. Jones as Carl
 * Ron Funches as Lola
 * Pamela Adlon as Franklin Zippington
 * Grey Griffin as Water Lily, Blitz Weathers
 * Wendi McLendon-Covey as Linda Peterson
 * Tom Kenny as Randy Peterson, Mr. Ross, Another Kid, Chess Player
 * Sumalee Montano as Helen McKean
 * Ana Ortiz as Lucy Malcolm
 * Susanne Blakeslee as Ms. Walker, Tour Guide
 * Jeff "Swampy" Marsh as Bubbles The Fish, Alligator
 * Dee Bradley Baker as Floppy, Big Chuck, General Zero, Zip Private, Pub-goer #2, Second Chess Player
 * Edie McClurg as Barmaid
 * Tress MacNeille as Pastrilum
 * Jonas Brothers as The Drolax Trio
 * Kevin Jonas as Amor Drolax
 * Joe Jonas as Basil Drolax
 * Nick Jonas as Cosmo Drolax
 * Bob Gunton as The Warden, from the Manhattan Prison
 * Patrick Warburton as Brock, one of the prisoners in Manhattan who helps Zoomie and Jolly escape from jail.
 * Bill Hader as Jim, a Native American zip person from the Manhattan Diner.
 * John Ratzenberger as Waiter
 * Brandon Greene as Buddy The Squirrel, Jerry, General Checker, Squiggly, Alien #2, Third Kid, British Man, Pub-goer #1, Paranoid darts player, Fly Followers
 * Tara Strong as Trifle, Kid
 * Jim Cummings as Chomper
 * Chandler Kinney as Beth Myers
 * Kevin Michael Richardson as Principal Zippwood, Dark Bucketman
 * Atticus Shaffer as Wolf
 * S. Scott Bullock as McZipper, Usher
 * Dieter Jansen as Mr. Thompson
 * Nolan North as Danny
 * Diedrich Bader as Ratman
 * Daran Norris as Mr. Rivers, Cop
 * Cree Summer as Mrs. Rivers, Lily (Mandy's cat)
 * Andy Milder as Mr. Davis
 * Kali Rocha as Mrs. Ross
 * John Morris Henson as Mr. Tinker
 * Kyla Greene as Mrs. Tinker, Leader of the Flies, British Mother, Announcer, Female Police Officer, Mother Bird
 * Charlie Schlatter as Beetle, Kid in bed, Security Guard #2
 * Jim Ward as Security Guard #1
 * Jim Ward as Security Guard #1