The Matthesons

The Matthesons is an American animated comedy series created by Carl Andy Jr. (under the name CAJ) that uses the 1988-89 anime adaptation of Osomatsu-kun by Fujio Akatsuka for the cable channel Comedy Central. Only 15 of the 86 episodes were aired before quietly being cancelled. It's main difference from the original version was it's reliance on American pop culture references and breaking the fourth wall as well as changing the setting from Japan to "An Ordinary American town that happens to have Japanese written all over it".