Doctor Octopus

Doctor Octopus (Dr. Otto Gunther Octavius), also known as Doc Ock for short, is a fictional character appearing in American comic books published by Marvel Comics. A highly intelligent and somewhat stocky and myopic mad scientist who utilizes four mechanical appendages for both movement and combat, the character debuted in The Amazing Spider-Man #3 (July 1963), and has since been featured as one of the most enduring foes of the superhero Spider-Man, which earned him a position as one of his archenemies. Doctor Octopus is notable for forming and leading the first supervillain team to oppose Spider-Man: the Sinister Six.

While usually portrayed as a supervillain, Doctor Octopus has also been occasionally depicted as a conflicted anti-hero and ally of Spider-Man, under the identity of the Superior Spider-Man. The first appearance of the Superior Spider-Man was briefly in Daredevil vol. 3 #21 (December 2012), with a full appearance in Avenging Spider-Man #15.1 the same month. In 2013, Marvel launched a 45-issue Superior Spider-Man comic book series, which saw Octavius taking the mantle of the Superior Spider-Man and struggling to become a hero after the original Spider-Man's death in "Dying Wish".

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 * Otto Octavius / Doctor Octopus appears in Marvel's Spider-Man: Webbed Champion, voiced by Scott Menville. His history in the show is the same as in the canon version. He serves as the primary antagonist of the first arc "City of Heroes", on which Octavius (after a battle against Spider-Man and Lady Octopus) had his consciousness to be transferred into cyberspace via the Neuro-Cortex, relocating himself into the Living Brain in the progress. He eventually begun operating as the Master Planner, manipulating a series of events to lure Spider-Man to his trap. His plan to relocate himself into Spider-Man's body eventually backfired when Spider-Man's armor optics (powered by Vibranium provided for Spider-Man by Black Panther) absorbed Octavius' consciousness and returned him back to his inactive body. From there, Octavius (while incarcerated back to the Cellar) attempted (but failed) to remember the codifications of the Neuro-Cortex and be rid of his memories from the past, such as his shame of remembering a failed experiment which rendered Carlie Cooper paraplegic. In "Seeds of Life", he was broken out of his cell and brainwashed as Madame Masque's servant until Spider-Man's team and the Avengers defeated her, rendering her powerless and freeing Octavius, who was also rendered physically disabled and mentally ill in the progress.
 * Doctor Octopus also appears in Marvel: All New, All Different Chronicles, voiced by C. Thomas Howell. He is a former Oscorp scientist who worked to perfect prosthetic limb technology and became a super-criminal called the Master Planner after four mechanical appendages were permanently attached to his back during an accident in his lab (it turned out to be an sabotage by Quentin Beck as an attempt to win Osborn's appreciation) which also killed his wife Rose, using an intra-cranial neural network to connect them to his nervous system. He was also once a brilliant, but neglectful science teacher in Midtown High School until he was fired and arrested after being exposed to public eyes by Spider-Man and his LMD (disguised as Peter Parker) for his crimes. After being broken out of his cell by Madame Masque and becoming a member of her Shadow Council, Octavius now operates in the alias of Doctor Octopus (or Doc Ock for short) while he still longs for revenge on Osborn for ruining his life.
 * Doctor Octopus appears in Marvel/DC Heroes Unite!, voiced by Fred Tatasciore. He serves as a boss in the main story, and as a playable character in the DLC story "Sinister Squads".
 * Doctor Octopus is an antagonist in Marvel's The Avenging Spider-Man, with William Salyers reprising his role.