The Toon-Night Show

The Toon-Night Show is a live-action/animation/puppet television series created by Seth MacFarlane and John Lasseter and featuring animated characters and puppet/animatronics characters from various studios. The series is set in a television studio in Hollywood.

Format
The premise of The Toon-Night Show is that Brain and Stewie (from Family Guy) are the hosts of a variety/talk show on ACME Studios. The show struck closely to the Muppet Show, House of Mouse, and Muppets Tonight format of various skits (mostly featuring the show's human guest star) interspersed with some sort of crisis occurring backstage.

Main Characters
Some familiar characters from other animated films, shows, and shorts appeared as members of the studio audience.
 * Brain Griffin and Stewie Griffin (both voiced by Seth MacFarlane) - Brain and Stewie serves as the hosts of the show since no one else wanted the job.
 * Twilight Sparkle (Voiced by Tara Strong) serves as the television producer of the show.
 * Taz the Tazmanian Devil (voiced by Jim Cummings) -
 * Louis (voiced by Sergio Di Zio) - Louis (from Wayside) serves as the janitor of ACME.
 * The Toon Patrol (voiced by David Lander, Rob Paulsen, Charles Fleischer, June Foray, and Fred Newman) - They appear as Bowser's assistant.
 * Carl Wheezer (voiced by Rob Paulsen) - Carl is often seen in cameos as a backstage crew member and has even made some audience cameos.
 * Phineas Flynn (voiced by Vincent Martella) - The young boy and inventor who shows off his inventions on the show.
 * Doc Brown (voiced by Dan Castellaneta) - Appears in the show.
 * The Fashion Club - A group of girls that star in "Great Moments in Fashion History."
 * Ferb Fletcher (voiced by Thomas Sangster) - Phineas' brother and assistant.
 * Roger Rabbit (voiced by Charles Fleischer) - A rabbit who serves as Rabbit's assistant.
 * Grumpy (voiced by Bill Farmer) - He serves as the janitor of ACME.
 * Kick Buttowski (voiced by Charlie Schlatter) - Kick does his stunt shows on the show.
 * Yakkity Yak (voiced by Lee Tockar) -
 * Guano (voiced by Gary Mack) - The scriptwriter of LilyMu who makes cameos as a crew member.
 * Candace Flynn (voiced by Ashley Tisdale)
 * Vanessa Doofenshmirtz (voiced by Olivia Olson) - She is Dr.Doofenshmirtz's daughter, Ferb has a crush on her.
 * Norm (voiced by John Viener)- A robot created by Dr. Doofenshmirtz.
 * Pepper Ann Pearson (voiced by Kathlenn Willhoite) (along with Nicky and Milo) serves as the production assistant of the show.
 * Nicky Little (voiced by Clea Lewis) (along with PA and Milo ) serves as the production assistant of the show.
 * Milo Kamalani (voiced by Danny Cooksey) (along with PA and Nicky) serves as the production assistant of the show.
 * Rowlf the Dog (performed by Bill Barretta) - He makes appearances playing pianos in some acts.
 * Squidward Tentacles (voiced by Rodger Bumpass) - He is host of his own segment.
 * Daria Morgendorffer and Jane Lane (voiced by Tracy Grandstaff and Wendy Hoopes) - Daria and Jane are usually seen commenting on the show from Daria's room.
 * Perry the Platypus (voiced by Dee Bradley Baker)
 * Louis (voiced by Michael-Leon Wooley) - An alligator who is seen assisting Taz in performing some songs.
 * Peter Rabbit
 * Toots the Horn from Bonkers
 * Derpy Hooves from My Little Pony Friendship Is Magic
 * Baby Puss from The Flintstones
 * The Wickersham Brothers
 * Gnu from The Muppet Show
 * Ice Cream Man from Lilo and Stitch
 * Tom Tucker from Family Guy
 * The Tookie Tookie Bird from George of the Jungle
 * Ape from George of the Jungle
 * Yo-Yo Flamingo from Fantasia 2000

Other Characters
Other characters included:
 * Mushu (voiced by Mark Moseley) - A Dragon who serves as the show's announncer.
 *  Dipper and Mabel Pines  (voiced by Jason Ritter and Kristen Schaal) Twin brother and sister gofers whose uncle Grunkle Stan owns the studio
 * Buzzie, Flaps, Ziggy, and Dizzy (voiced by Jim Cummings, Jeff Bennett, Baron Davis, and Jess Harnell) - A group of four vultures that make up their own barbershop quartet.
 * Big Mean Carl (performed by Bill Barretta) - A shaggy monster who is in the category of Muppets eating other Muppets. He also makes audience appearances.
 * SpongeBob SquarePants (voiced by Tom Kenny) - SpongeBob SquarePants the sea sponge who blows bubbles for fun.
 * Ed (voiced by Matt Hill) - A tall, strong, dimwitted boy who works as a security guard.
 * Orson (Voiced by Gregg Berger) - A pig who serves as the captain of the Toontrek
 * Hector Con Carne (voiced by Phil LaMarr) -  He is a dynamic, evil playboy type, reduced to an anthropomorphic brain and a stomach after a gigantic explosion He is a crew member on the Toontrek
 * Boskov ( voiced by Frank Welker) -  A former Russian circus bear, Boskov carries Con Carne's brain and stomach on his body, via metal plates on said spots, He is a crew member on the Toontrek
 * Wade ( voiced by Frank Welker) - A duck who appears in the" Deep Toon Nine" segments
 * May Kanker ( voiced by Erin Fitzgerald) She appears in the "At the Malt Shop " sketch co-owning a Malt Shop with her Sisters
 * Stacy Hirano (voiced by Kelly Hu) - She was featured in "The Real World Toons " segments.
 * Johnny Bravo ( voiced by Jeff Bennett) - is the star of "Bay of Watch.
 * Professor von Kripplespac - a doctor that appeared on "E-I-E-I-O R."
 * Dr. Heinz Doofenshmirtz (voiced by Dan Povenmire) -  A mad scientist who hosts "Tales from the Lab"
 * Bowser (voiced by Scott Burns) - He is the Chairman and CEO of The Koopa Group which bought out the studio
 * Wendy (voiced by Linda Cardellini) - The floor manager of ACME Studios who Dipper has a crush on.
 * Gary Cahuenga (performed by Dave Goelz) - A ventriloquist 's dummy with a mind of his own.
 * Grunkle Stan (voiced by Alex Hirsch)- Dipper and Mabel's great uncle and Brain and Stewie's boss at ACME.
 * Garfield (voiced by Frank Welker) - A rich food-loving cat who was featured in "The Tubmans of Catsmith."
 * Mr. Herriman (voiced by Tom Kane) - Garfield`s butler.
 * Trinket St. Blair (voiced by Jenna von Oy) - A  singer, she is rich and spoiled.
 * Cissy Rooney (voiced by Kath Soucie)- A popular airhead, she serves as Trinkets`s flunky, bodyguard, and assistant.
 * Soos (voiced by Alex Hirsch) - A crew member at ACME.
 * Zazu (voiced by Jeff Bennett) - A bird who leads the Toon-Night Show Band
 * Pops (voiced by Sam Marin) - An eccentric character with a strange fashion style.
 *  Toon-Night Show Writers - A group of three monkeys who did the writing for the show.
 * Rabbit (voiced by Tom Kenny) - He serves as the show's stressed-out director.
 * Snoopy (voiced by Cam Clarke) - A dog who serves as the elevator operator and commissary cook . He is often paired up with Tantor.
 * Lee Kanker (voiced by Janyse Jaud) She appears in the "At the Malt Shop " sketch co-owning a Malt Shop with her sisters.
 * Marie Kanker (voiced by Kathleen Barr) She appears in the "At the Malt Shop" Sketch co-owning a Malt Shop with her Sisters.
 * Ickis - A monster who appeared in unnamed appearances in this show.
 * Tantor (voiced by Jim Cummings) An elephant who serves as the elevator operator and commissary cook . He is often paired with Snoopy.
 * Snookie Blyer (performed by Bill Barretta) - The host of the game show "Swift Wits.
 * Holli Would (voiced by Kim Basinger) - She was featured in Bay of Watch.
 * Zeus (voiced by Corey Burton) - The God of Thunder who is seen doing every day mundane tasks. Whenever someone angered him, Zeus would strike the person with lightning.
 * Craig Bean (voiced by Jeff Bennett) -  is one of the crew members on the show who Pepper Ann has a crush on.

Episodes

 * List of The Toon-Night Show episodes