Villains in Pandora's Box

Pandora's Box is so full of evil contents, including:
 * Chaos (Dissidia)
 * Satan
 * Cthulhu
 * Xenu
 * Galactus
 * Unicron
 * Dark Specter
 * Infinity Sword
 * Dark Phoenix Force
 * Soul Edge
 * Anti-Monitor
 * Darkseid
 * Shao Khan
 * Thanos
 * Tai Lung
 * Master Xandred
 * Baron Silas Greenback
 * Megatron
 * Gargamel
 * Bill Cipher
 * Nightmare Moon
 * Mephiles the Dark
 * Agent Smith
 * Slappy the Dummy
 * Darth Vader
 * Flurious
 * Moltor
 * Kamdor
 * The Fearcats
 * Sledge
 * Fury
 * Poisandra
 * Wrench
 * Curio
 * Vrak
 * Prince Vekar
 * Emperor Mavro
 * Gaston
 * Jafar
 * Maleficent
 * Ursula
 * Hades
 * Cruella de Vil
 * Lady Tremaine
 * Evil Queen Grimhilde
 * Ratigan
 * Dark Surfer
 * Cervantes De Leon
 * Blackbeard
 * Islamic State of Iraq and Syria (ISIS)
 * The Illuminati
 * Cobra Commander
 * Wrath-Amon
 * Makuta Teridax
 * Shendu
 * Shredder
 * Lotso
 * Cain (The Bible)
 * And a lot of others!