Rampage 2: Destruction Tour (2019)

Davis Okoye is called again to the OGA led by Harvey Russell to help captured or terminate any giant monsters created by the Energyne's Alternative Research Laboratory. Also, George the Gorilla is getting some unexpected friends to help battle the Energyne's monsters and save the world.

Plot
After the events in Chicago, the pathogen canisters from the destroyed space station (Athena-1) is recovered by Zee Wyden (Claire & Brett Wyden's uncle) and his son (Vern Wyden). Zee Wyden plans to restart the Project: Rampage and selling his weapons to the highest bidder.

Main Characters

 * Davis Okoye (portrayed by Dwayne Johnson): A primatologist and head of an anti-poaching unit, he and George must battle the Energyne's monsters with some unusual allies.
 * Lawrence Bane (portrayed by Taron Egerton): A former employee of Energyne's Alternative Research Laboratory and undercover agent of OGA who helped Ralph Jr. escape a secret Energyne's Alternative Research Laboratory in Arizona. Lawrence deeply care for Ralph Jr. and overly protective his best friend.
 * Dr. Elizabeth "Beth" Veronica (portrayed by Zoe Saldana): A herpetologist and reptile fanatic, she is a rival towards Davis and "mother" of Liz the Lizard.


 * Harvey Russell (portrayed by Jeffrey Dean Morgan): A government agent of OGA and supervisior of the Wrecking Crew.

Main Villains

 * Zee Wyden (portrayed by Mark Strong): The head CEO of Energyne, he rebuilt the company from his niece and nephews mistakes by running a bio-weapons trade.


 * Dr. Eustace Dee Montic (portrayed by Danny DeVito): A leading scientist of Energyne's Alternative Research Laboratory before becoming a CEO of his own company.
 *  Vicky Nickson (portrayed by Yancy Butler):

The Monsters
Wrecking Crew: A trio of monsters assemble by agent Harvey Russell and George is the leader of the trio, only two monsters later align with them.


 * George (portrayed by Jason Liles): A 30 foot tall albino gorilla (based on Snowflake (gorilla)) mutated by the Project: Rampage's chemical and leader of the Wrecking Crew. He is a humorous private and often jokily play with Davis for laughs, his mutation given him a little heighted intelligence since is coordinated his "troops" in battle or caring for their safety.
 * Ralph Jr. (sound effects by Eric Bauza): A 35 foot tall Lupo Italiano (Italian wolfdog) who is injected with blood of the mutated wolf (original Ralph) by Dr. Eustace Dee Montic, he is given the "Chill Pill" to subdue his enrage nature and only reaching to 14 feet as puppy and under care of Lawrence. A year later, the subject dubbed "Ralph Jr." developed a bond for Lawrence and breaking out his caged to protecting him from the giant mutant Crab (one of Ruby's offspring). Lawrence help Ralph Jr. escapes the Arizona's Energyne's Alternative Research Laboratory during the chaos of the Energyne's animals escaping, he is allowed to live if his assistance for the OGA under Harvey's supervision and Lawrence as his handler. Like Ralph of the first film, he has quills on his back, bushy tail with quills, gliding membrane like a flying squirrel, long legs and body of a wolf.
 * Liz the Lizard: A baby Argentine Black and White Tegu who was exposed to the gases from the Project: Rampage's canister in the street of Rio, she is found by Beth (a herpetologist) and becoming a faithful giant pet. As a 50 foot long and 30 foot wide lizard, she is a main attraction of Brazil's nature preserve and living in her own enclosure. Due to being mutated as baby, her skin color is emerald green with a yellow under belly. Liz has a yellow spike crest on her head to back, red eyes, a black tongue and resembling a komodo dragon.
 * Francis the Bat: A giant Fruit Bat with ability to grow endless supply of giant plants with fruits by spitting out seeds coated in saliva he collected of trees in the Amazon.

Energyne's Monsters: They are rogue mutated animals loosed around the states and the Wrecking Crew is send to stop the monsters.


 * Leon the Lion: A giant mutant lion with Chimera traits, he was mutated by the gases from the Project: Rampage's canister dropped in his enclosure in the San Diego Zoo by disgruntled ex-employee of Energyne. Leon in his 10 foot tall first form is muscular forelimbs with two spikes on his head and rat-like tail, he escaped from the zoo and hides in California's Elfin Forest. Leon in his 20 foot tall second form has two forward curved horns, messy mane, hoof-like claws on his back legs and pointed upper canine teeth, he is seen eating a farmer lost cattle herd. In his 48 foot tall final form has a Smilodon with a blade-like exceptionally long upper canine teeth and robust body, goat-like horns, hoof-like claws on his back legs and a lizard tail surround with spike quills. Leon attacks Las Vegas and battles Boris. Leon's head is crushed to death by Boris's feet.
 * Sarah the Wolf Spider : A giant mutant spider with wolf traits.
 * Gilman the Fish: A giant mutant blowfish (resembling more of Toadfish).
 * Ruby the Crayfish: A giant mutant 28 foot tall crayfish with a rocky exoskeleton and the ability to eating rocks, tar, cement, granite and especially rubies (hence her name)
 * Robby the Crayfish: Son of Ruby and a six foot tall crayfish devour by Ralph Jr.

Monsters Cameo


 * Ralph the Wolf: Ralph's blood is used on a wolfdog puppy (Ralph Jr.) to recreating another bio-weapon and the blood sample is recover by one of Eustace's scientist. Ralph's skeleton is displayed in the British History Museum and his skull is recovered from Lizzie's stomach, his skeleton is displayed in a gliding position in forest setting.
 * Lizzie the Crocodile: Lizzie's skeleton is displayed in the American Museum of Natural History and referring as "Godzilla's cousin of the South".
 * Larry the Rat: A picture is shown on Vern's cellphone.
 * Shelby

Trivia

 * 1) Two mutant animals are named after Ralph and Lizzie.