Sanity

 is an American animated action television series created by Craig McCracken. It is produced by and premiered on Cartoon Network from 2005 to 2007.

Synopsis
The series follows detective, his partner and a dog traveling worldwide solving mysteries, while they are fighting their foes.

Main

 * Detective William Topps (voiced by Tom Kane) - a private detective who solves mysteries and the main protagonist.
 * Buddy (voiced by Frank Welker) - a german shepherd who is Detective Topps' loyal talking pet.
 * James Alroy (voiced by Rob Paulsen) - a teenager who is Detective Topps' partner and a mechanic.

Allies

 * Alissa Summers (voiced by Grey DeLisle) - a female police officer who helps the heroes to their mysteries.
 * Mayor Chuck (voiced by Tom Kenny) - a dim-witted man who is the peaceful mayor of Santa Carolina.
 * Professor Jeremiah Topps (voiced by TBD) -
 * Fiona Alroy (voiced by TBD) -
 * Mr. and Mrs. Alroy (voiced by TBD) -

Villains

 * Mr. Vin-Vang Wong (voiced by Kirk Thornton) - a Chinese overweight man who is the CEO of a company and the main antagonist.
 * Stephanie Mota (voiced by Tara Strong) - a Buttercup-like young woman who is the one of Mr. Vin-Vang Wong's henchmen.
 * Ivan Vanako (voiced by Maurice LaMarche) - a Russian thief who likes to steal animals and turn them into clothing.
 * Napoleon Napoleon (voiced by Jeff Bennett) - a Napoleon-like French thief who is a biggest fan of Napoleon.
 * Casandra Summers (voiced by E.G. Daily) - a corrupted woman who is Alissa's former sister and joined forces with Mr. Vin-Vang Wong.
 * Mr. E (voiced by Roger L. Jackson) - a mysterious Spanish man who doesn't like to reveal himself.
 * Princess Emily (voiced by Jennifer Hale) - a tough to be nice British princess who actually is a rich girl.

Episodes
See List of episodes

Trivia

 *  is inspired by Hanna-Barbera's Scooby-Doo, Droopy, Master Detective and Snooper and Babbler, Disney's Darkwing Duck, DIC Entertainment's Where on Earth is Carmen Sandiego? and Sherlock Holmes in the 22nd Century, Steve Purcell's Sam & Max, Sony Pictures Television's Phantom Investigators and Warner Bros' The Sylvester & Tweety Mysteries.
 * In 2015, Craig McCracken confirmed that the series will have a sequel series to schedule 2017.
 * In every episode, James is always confusing words on Detective Topps, such as "what" for "hat".
 * The three vehicles are the World-Jet (for air), the Toppsmobile (for ground) and the Ocean Sub 3000 (for sea).