Earth-646 Marvel Universe

The Earth-646 Marvel Universe is a more down-to-Earth, mature version of the Super Hero Squad Universe that is a mix of the Marvel Cinematic Universe, the Avengers: Earth's Mightiest Heroes Universe, X-Men: Evolution, the Ultimate Marvel Universe, the Marvel Anime Universe, and plenty more.

Asgardian Times
Years after the Big Bang, there was a war between the Asgardians and the Frost Giants from Jotunheim. However, this feud ended when the ruler of Asgard, Odin, decided to take a newborn son (who would then be named Loki Laufeyson) as a peace offering between the two realms. As time passed, Odin and his spouse Frigga brought up their firstborn child, Thor Odinson, who would be good friends and companions with his adopted brother Loki. The two brothers would later on be trained by their parents to either learn how to use magic (Frigga to Loki) or learn how to fight like a true warrior (Odin to Thor). After reaching adulthood, Thor would then receive the godlike hammer Mjolnir, but he and his brother Loki would go their seperate ways and head to different paths.

World War II
In New York City, December 1941, Steven Grant Rogers would get constantly rejected in joining the United States, due to his fraility and health issues. Though, Rogers' determination caught the attention of Dr. Abrham Erskine, who would then enlist young Rogers into Project: Rebirth and transform him into the world's first Super Soldier: Captain America. The Captain became a living icon to those who wish to enlist in order to serve their country, and would lead the Howling Commandos, along with his fellow companion James Buchanan Barnes, against the tyrannical Red Skull and his massive army of HYDRA soldiers. However, after a hard fought battle, Captain America's whereabouts were left unknown.

Present Time
Obadiah Stane, and later on, Anthony Antonio Stark took over as CEO of Stark Inudstries after the deaths of both Howard and Maria Stark. After Stark Industries came to light, other companies such as Roxxon, Octavius Labs, Fisk Industries, Hammer Industries, and Oscorp would be at arms with the company. However, this would also the time when Stark was captured by a terrorist organization known as the Ten Rings.