Rise of the Powerpuff Girls

The Powerpuff Girls Rises is an upcoming American animated superhero film based on the Cartoon Network animated television series The Powerpuff Girls (2016 reboot series). It was directed by the series' developer Nick Jennings and Bob Boyle (in their directorial debut), it stars the regular television cast of Kristen Li, Amanda Leighton, Natalie Palamides, Roger L. Jackson, Olivia Olsen, Tom Kenny, and Jennifer Hale; as Zach Callison, Willem Dafoe, and Natalie Portman joined the cast to voice the new characters in the film.

It'll be the sequel/reboot of the 2002 film The Powerpuff Girls Movie, the last film in the Powerpuff Girls series, the series finale to The Powerpuff Girls (2016 series), and the series finale for the entire animated Powerpuff Girls franchise. It'll produced by Columbia Pictures, Legendary Pictures, Cartoon Network Studios, Atlas Entertainment, and Tencent Pictures, and set for distribution by Warner Bros. Pictures and co-distributed by Sony Pictures Releasing.

The Powerpuff Girls Rises will be theatrically released in the United States on IMAX, 4DX, and Dolby Cinema on August 26, 2022. It was multiple delays from the November 2020 release date due to both unknown reason and COVID-19 pandemic. It'll be the first film to be produced by Cartoon Network Studios after 20 years since the release of The Powerpuff Girls Movie (2002).

Premise A Powerful Villain has taken over Townsville and is planning to destroy all kinds of the world. As The Powerpuff Girls will be ready for their final confrontation to save the world as Bubbles would know if she always what it takes to be a hero.

Cast Kristen Li as Bubbles Utonium

Amanda Leighton as Blossom Utonium

Natalie Palamides as Buttercup Utonium


 * Natalie also voiced Barbarus Bikini (vocal effects)

Zach Callison as Javier (a new character for the film). Zach previously voiced Steven Universe in the Cartoon Network show of the same name.

Willem Dafoe as a unnamed Masked Man

Natalie Portman as TBA

Roger L. Jackson as Mojo Jojo

Olivia Olsen as Blisstina Utonium

Tom Kenny as the Mayor of Townsville


 * Tom also voiced the Narrator, Snake, and Lil' Arturo

Jennifer Hale as Ms. Keane

Tom Kane, the voice of Professor Utonium and HIM will have the un-used archive recording from both the original and the reboot of the series since he retired voice acting due to his stroke in November 2020.

Chuck McCann who voice The Amoeba Boys will have the un-used archive recording from the original series since Chuck passed away on April 8, 2018. This film will be dedicated to his memory.

Additionally, cast from the original and reboot will reprise their roles, including Jim Cummings as Fuzzy Lumpkins, Haley Mancini as Princess Morbucks, Jason Spisak as Packrat and Silico, Jessica DiCicco and Kate Higgins as Maylyn and the Derbytantes, Jeff Bennett as Ace, Grubber, and Big Billy, Lily Vonnegut as Bianca, Maurice LaMarche as Manboy, and Josh Fadem as Donny. Anais Fairweather has been cast in a undisclosed role.