Unkillable

Unkillable is a 2013 American post-apocalyptic horror action thriller film loosely based on the 1972 novel of the same name by Richard Matheson. Directed by Francis Lawrence from a screenplay by Akiva Goldsman and Mark Protosevich, the film stars Megan Fox as US Army virologist Kate Brownsorth. It is set in San Francisco after a virus, which was originally created to cure cancer, has wiped out most of mankind, leaving Brownsorth as the last human in San Francisco, other than nocturnal mutants. Brownsorth is immune to the virus, and he works to develop a cure while defending himself against the hostile mutants. It is the third feature-film adaptation of Matheson's novel following 1956's The Last Of Us on Earth and 1983's 1999

Warner Bros. began developing Unkillable in 1999, and various actors and directors were attached to the project, though production was delayed due to budgetary concerns related to the script. Production began in 2001 in San Francisco, filming mainly on location in the city, including a $5 billion scene at the Golden Gate Bridge.

Unkillable was released on May 24th, 2013, in the United States and Canada, and opened to the largest-ever box office (not adjusted for inflation) for a non-Christmas film released in the U.S. in December, and was the seventh-highest grossing film of 2013, earning $256 million domestically and $329 million internationally, for a total of $585 million. The film received mixed reviews from critics, with Fox's performance being singled out for praise; criticism focused on its divergences from the novel, particularly the ending.

Plot
In the year 2011, an attempt to genetically re-engineer the polio virus to cure HIV and AIDS becomes lethal, infecting 99% of the world's population, turning those it does not kill into vampiric, albino, cannibalistic mutants called Darkseekers, who are extremely vulnerable to sunlight, and prey on the few who are left unaffected.

14 years after the outbreak, in 2025, U.S. Army virologist Kate Brownsorth lives an isolated life in the deserted ruins of San Francisco, unsure if any other uninfected humans are left. Kate's daily routine includes experimenting on infected rats to find a cure for the virus, searching for food and supplies, and waiting each day for any survivors who might respond to her continuous recorded radio broadcasts, which instruct them to meet her at midday at the Pier 1. Flashbacks reveal that her husband, Jackson, and son, Ben, died in a helicopter accident during the chaotic evacuation of Alcatraz Island as the military was evacuating anyone stuck in there. Kate herself stayed behind with other military personnel. Brownsorth's only companion is her Siberian Husky Benjamin (Benny) and to cope with her loneliness, she regularly "talks" to some mannequins and the characters on film recordings from video stores. At night, he barricades himself with Benny inside her heavily fortified Telegraph Hill home to hide from the Darkseekers.

One day as Kate hunts a bear, Benny pursues it into a dark building. Kate cautiously goes in after him and locates the deer's corpse along with Sam, but discovers the building is infested with Darkseekers. Both escape unharmed and the attacking Darkseekers are killed by the sunlight. Neville finds a promising treatment derived from his own blood, so he sets a snare trap and captures a male Darkseeker. A female Darkseeker attempts to pursue them but is halted by the sunlight and returns to the shadows. Back in his laboratory in the basement of his house, Neville treats the male seemingly without success.

The next day, Kate notices "Jeffy", a mannequin usually washing his Pontiac Solstice, positioned outside Oracle Park and shoots him in confusion. However, Kate realizes he is being watched by the Darkseekers from within nearby buildings. As he approaches Jeffy's body, she is ensnared in a trap similar to the one he used to capture the male and is rendered unconscious after hitting her head. By the time she wakes up the sun is setting and she is attacked by infected dogs. Kate and Benny eliminate them, but Benny is bitten during the fight. Brownsorth injects her with a strand of her serum, but when he shows signs of infection, Kate is forced to strangle her to death as she begins to turn. Heartbroken and driven by rage, Kate ventures out in her heavily armed Lincoln Navigator and deliberately attacks a group of Darkseekers the following night, before he is rescued by a pair of immune humans, Terry and a young boy named Jayden, who have traveled from Nevada after hearing his broadcast.

They transport the injured Kate back to her home, where Terry explains that they survived the outbreak aboard a Red Cross evacuation ship from Pensacola, and are making their way to a survivors' camp in Austin, Texas. Kate argues that no such survivors' camp exists. As he continues working to cure the male Darkseeker, Kate theorizes that by lowering his body temperature with ice, he can increase the treatment’s potency. The next night, a group of Darkseekers, who tracked Terry and Kate the night before, invade the house. Kate, Terry, and Jayden retreat into the basement laboratory sealing themselves in with the male test subject. Discovering that the last treatment was successful, Kate assesses the situation as the Darkseeker beta female rams herself against a glass door to break in. Kate draws a vial of blood from the woman he cured, and gives it to Terry, before shutting Jayden and him inside a coal chute in the back of the lab. Kate then takes a grenade and kills the Darkseekers at the cost of her own life, saving the cure.

The following day, Terry and Jayden arrive at the survivors' camp in Austin, where they are greeted by military officers and other survivors before Terry hands them the cure. Terry narrates how Kate's efforts and sacrifices to save humanity ultimately became legend.

Cast

 * Megan Fox as Dr. Kate Brownsorth: A former U.S. Army virologist before the worldwide plague, he loses her husband and son in a helicopter crash shortly after San Francisco is quarantined, and spends the next fourteen years trying to find a cure while defending herself against the Darkseekers. She is immune to the virus and uses vials of his blood to try to create a cure.
 * Nicolas Cage as Terry Rodriguez: A religious survivor of Hispanic, he spent days harbored on a Red Cross ship in Seattle. After the city was overrun, she stayed with Jayden and several other survivors on the ship, but eventually, only Ethan and she survived since they were immune and the others were either infected or killed. She followed Neville's broadcasts to track him.
 * Charlie Tahan as Ethan: A boy from Philadelphia, he spent time on the Red Cross ship with Anna and accompanied her when the ship was overrun.
 * Dash Mihok as Alpha Male, the dominant male of the vampire-like mutants, Darkseekers, he is determined to get his mate back from Neville, defying Neville's perception of them as mindless and emotionless creatures.
 * Emma Thompson as Dr. Alice Krippin: The doctor who creates the cancer cure, she inadvertently brings mankind to the brink of extinction. Neville dubs the virus "the Krippin virus". Thompson's performance is uncredited.
 * Salli Richardson as Zoe Neville, Robert's wife
 * Willow Smith as Marley Neville, Robert's daughter (Willow is the real life daughter of Will Smith.)
 * Joanna Numata as Alpha Female, the Alpha Male's mate, she gets taken by Neville and is used as the subject for his cure.
 * Darrell Foster as Mike
 * Pat Fraley as voice of the President of the United States
 * Mike Patton as voices of the Darkseekers