Howler 5: Night of the Cthulhu

 is an American supernatural-comedy video game, being the fifth installment of the Howler video game series. It is developed and published by Warner Bros. Interactive Entertainment and was released on October 27, 2017.

Main

 * Jeffrey Morrison/Howler (voiced by Charlie Schlatter in his human form and Kevin Michael Richardson in his werewolf form) - a shy and well-meaning young adult who can turn into a werewolf at full moon, being out to revert his state while he fights threats whenever he has to.

Supporting

 * Bella Stoker (voiced by Jennifer Hale) - a generally kind vampire who is Howler's love interest, often aiding him.
 * The Ghost Twins, consisting of:
 * George (voiced by Jeff Bennett) - a ghost boy who is usually happy and likes to goof off.
 * Georgia (voiced by Kat Cressida) - a ghost girl who, unlike George, is more serious and more mature. However, even so, she still cares about her brother.
 * Frank N. Stein (voiced by John DiMaggio) - a frankenstein monster who is unintelligent. Despite that, however, he gets random bursts of intelligence. It is later explained by Bella Stoker that he has "multi-intelligence disorder", making him smart at times and stupid at other times.
 * Greg (voiced by Doug Lawrence) - a gargoyle who is immature and is usually a narcissist.
 * Lex the Lynx (vocal effects by Dee Bradley Baker) - a dimwitted lynx who acts like a cat and loves to play. He was rescued by George when a grizzly bear tried to eat him once.

Antagonists

 * The Cthulhu (voiced by Michael Dorn) - a giant octopus-human-dragon hybrid who aims on enslaving mankind.
 * Angelica, Sergei and Buddy (voiced by Kari Wahlgren, Rob Paulsen, and Charlie Adler, respectively) - a trio of imps who love to cause chaos.