Spider-Man: The Web of Two

Spider-Man: The Web of Two is an animated series based on Marvel Comics, airing on Hulu. It is set in the continuity of Insomniac Games' video game franchise.

Premise
Set five months after Tinkerer's sacrifice and Simon Krieger's arrest, Peter Parker and Miles Morales head to protect New York from its criminal underworld as the city's Spider-Men.

Main

 * Peter Parker / Spider-Man (voiced by Yuri Lowenthal) - A scientist who earned his spider-powers from a radioactive spider bite, and has been Spider-Man for 8 years before Miles got his powers. He mourns the loss of his uncle Ben and more recently his aunt May, but still stands tall for what is right.
 * Miles Morales / Spider-Man (2) (voiced by Nadji Jeter) - A teenager and Peter’s protégé who earned his spiderpowers from a second, advanced lab spider which gave him the same powers as Peter, along with his long abilities of Venom Strike and camouflage. He mourns the deaths of his father Jefferson Davis and childhood friend Phin Mason, but like Peter, still stands tall on his duties as Spider-Man.

Supporting

 * Mary Jane "MJ" Watson (voiced by Laura Bailey) - Peter's girlfriend, and a Daily Bugle reporter who has been aware and supportive of his identity of Spider-Man, and mutually supports Miles.
 * Carlie Cooper (voiced by Mae Whitman) - A teenage Daily Bugle intern who is MJ's protégée.
 * Ganke Lee (voiced by Griffin Puatu) - Miles' best friend who is aware of his identity of Spider-Man as he attempts to help him out when he can.
 * Rio Morales (voiced by Jacqueline Piñtol) -
 * Hailey Cooper -
 * Felicia Hardy / Black Cat (voiced by Erica Lindbeck) - A cat burglar who has an attraction for Spider-Man although she is seemingly attempting to go semi-clean.
 * Lana Baumgartner / Bombshell (voiced by Ashley Johnson) - Black Cat's protégée, and a teenager with the abilities of flight and Energy Blasts with explosive effects or Shockwave. She is considered as Miles's counterpart.
 * Dr. Morgan Michaels / The Vampire (voiced by Phil Morris) -
 * Gloria Davila (voiced by Melanie Minichino) - the current manager of FEAST after May's death and Li's arrest who attempts to help those in need.
 * Danika Hart (voiced by Ashly Burch) - The host of the podcast series The Danikast who discusses recent topics in New York, and is positive towards Spider-Man, spreading good news about his work around the city.

Antagonists

 * Mayor Norman Osborn/The Big Man / The Goblin (voiced by Mark Rolston) - The mayor of New York who is slowly turning insane, soon holding a grudge on Spider-Man, blaming him for all that is wrong with the city.
 * Harry Osborn / Black Goblin (voiced by Scott Porter) - Peter's and Mary Jane's best friend who is terminally ill, and being subjected to a lab experiment meant to save his life, turning twisted and extremely vicious.
 * Wilson Fisk / The Kingpin (voiced by Travis Willingham) - New York's most ruthless crime lord, and one of Spider-Man's oldest foes.
 * Yuriko "Yuri" Watanabe / Wraith (voiced by Tara Platt) - Spider-Man’s former contact in the Police Force who has become a murderous vigilante, believing that no criminals are allowed to live and nobody can be redeemed.

Minor

 * Otto Octavius (voiced by William Salyers) - Peter's former employer and mentor who became Doctor Octopus after the use of his tentacle harness drove him insane. Imprisoned following his defeat, he is now occasionally visited by Peter, and more recently carries out regret for his actions, which resulted in the death of Peter's aunt May.
 * Stan (voiced by Stan Lee through archive audio dialogue) -
 * May Parker (voiced by Nancy Linari) - Peter’s deceased aunt. She appears in flashbacks of Peter's memories.
 * J. Jonah Jameson (voiced by Darin De Paul) - the head of the podcast known as Just the Facts who actively dislikes Spider-Man yet cares for the city.