Let's Go, Scooby-Doo!

Let's Go, Scooby-Doo! is a 2020 animated series created by Warner Bros. Animation.

Plot
"In 'Let's Go, Scooby-Doo!', the Mystery Gang embarks on a globetrotting adventure, joined by new friends, Tom, Jerry, Sylvester, Tweety, Ruffy-Doo, Riff Jones, Wally Rogers, Bridget Blake, and Madelyn Dinkley. Their quest to solve mysteries takes them to exotic locations, from haunted castles in Transylvania to treasure-filled tombs in Egypt. But there's a twist – Shaggy can transform into 'Shagwolf,' adding a new dimension to their investigations. Together, they unravel perplexing mysteries, encounter classic foes, and forge unforgettable friendships in a world where laughter, courage, and teamwork reign supreme. 'Let's Go, Scooby-Doo!' is a rollercoaster ride of humor, heartwarming moments, and thrilling enigmas that will keep viewers of all ages on the edge of their seats!"

Mystery Gang

 * Scooby-Doo (voiced by Mason Klusek): The main protagonist of the series, and the main mascot of the Mystery Gang. Unlike most incarnations, he can now speak in complete sentences, and can speak perfect English. While he is still cowardly, dimwitted and food-loving in this series, Scooby-Doo is now also more down-to-earth, easy-going, yet intelligent and wise. He and his cousin Ruffy would usually act as a duo of dog detectives (similar to Woofer and Wimper from Clue Club). His main catchphrase is "Scooby-Dooby-Doo!". Scooby-Doo's newfound down-to-earth nature brings a grounded perspective to the gang, offering valuable insights and wisdom in moments of crisis. Despite his goofy exterior, Scooby becomes a source of comfort and advice for the team. Scooby's love for food takes center stage, and he develops an interest in diverse cuisines, often showcasing his refined palate during the gang's travels. His culinary adventures become a running subplot, with the gang discovering unique local dishes in each mystery location. Scooby surprises the gang with occasional bursts of intelligence, showcasing a hidden cleverness that aids in solving mysteries. His ability to connect seemingly unrelated clues becomes a valuable asset, adding an element of unpredictability to the investigations. The dynamic between Scooby and his cousin Ruffy as a duo of dog detectives creates entertaining and adventurous moments within the group. Their teamwork and camaraderie contribute to the success of the gang's missions, with Scooby's experience and Ruffy's enthusiasm complementing each other. Scooby's classic catchphrase "Scooby-Dooby-Doo!" takes on various forms depending on the situation, showcasing his versatility in expressing emotions. The catchphrase becomes a humorous and adaptable element, adding a touch of playfulness to different scenes. Scooby's bond with each member of the gang is highlighted through unique interactions, showcasing moments of friendship, loyalty, and occasional comedic misunderstandings. Scooby, despite his initial fear, occasionally rises to the occasion with heroic feats, surprising the gang and proving that bravery can emerge in unexpected circumstances. These moments add layers to Scooby's character, emphasizing that courage can be found even in the most unlikely places.
 * Ruffy-Doo (voiced by Josh Keaton): Scooby's dalmatian cousin and best friend. He is based on the old character Scrappy-Doo. Ruffy has some of Scrappy's signature traits, like his confidence, bravery, and eagerness to solve mysteries. However, he is also clever, friendly, protective, sometimes sneaky, and happy-go-lucky. Ruffy is the energetic and adventurous member of the gang, always ready to dive into action, but his enthusiasm can lead to both solutions and challenges during investigations. Ruffy likes to learn important lessons in life. He also has a keen sense of smell. His favorite snacks are "Ruffy Yum-yums". His main catchphrases are "Ruffy-Duffy-Doo!", "Doggy Power!" and "Let me at 'em!". Ruffy has a passion for solving puzzles and enjoys challenging brainteasers, making him the go-to member when the gang encounters complex mysteries. He's surprisingly skilled at navigating mazes, whether they're physical or metaphorical, showcasing his quick thinking and adaptability. Ruffy has a collection of adventure gear, including a mini backpack filled with gadgets and tools he finds useful during investigations. Ruffy is exceptionally protective of Scooby and his human friends, displaying a loyal and brave side when danger arises. Despite his small stature, he has a knack for coming to the rescue just in the nick of time, surprising everyone with his courage. Ruffy, being a dalmatian with a mischievous streak, occasionally uses his spots to blend into his surroundings during stakeouts or sneaky investigations. His clever disguises and stealthy maneuvers often catch villains off guard, contributing to the gang's success in solving mysteries. Ruffy, despite his energetic nature, values wisdom and often imparts insightful life lessons to the gang when facing challenges. He might share proverbs or anecdotes that, in a lighthearted way, help the gang understand the importance of teamwork and perseverance. Ruffy has a special bond with each member of the gang, sharing heartwarming moments that strengthen their friendship. His interactions with Scooby are particularly entertaining, as they often team up for comedic and daring antics.
 * Norville "Shaggy" Rogers (voiced by Nick Palatas): Scooby's owner and other best friend. His personality is a mix of those of his original and "Be Cool, Scooby-Doo!" counterpart. Like in most incarnations, Shaggy is a cowardly slacker more interested in eating than solving mysteries. He is the cowardly and lazy member of the group who likes baggy clothing, and can turn into his reluctant werewolf form, Shagwolf, every time he sees the full moon or something related to the moon. In this series, he appears to have a crush on Bridget. In "Scooby-Doo and the Reluctant Werewolf", Shaggy decides to keep his werewolf form and transform the same way as Fangface did. However, unlike Fangface, Shagwolf knows that he and Shaggy are the same being. His main catchphrase is usually "Zoinks!" Both Scooby and Shaggy can be easily bribed with "Scooby Snacks" in order to act as the gang's live bate when it comes to catching kooks. The reason Shaggy eats so much (and maintains his slender physique) is his "high metabolism". He is also very fond of baseball, having grown up watching the Gypsy Moths at a young age. Shaggy's high metabolism becomes a recurring element, allowing him to indulge in copious amounts of food without gaining weight. The gang humorously navigates Shaggy's insatiable appetite, with his constant snacking leading to unexpected advantages in certain situations. Shaggy's love for baseball becomes a nostalgic subplot, with the gang occasionally stumbling upon mysterious baseball-related mysteries that harken back to his childhood. His knowledge of baseball trivia unexpectedly aids in solving one of the mysteries, showcasing the practical side of his interests. Shaggy's werewolf form, Shagwolf, adds a unique twist to the mysteries, with his occasional transformations contributing to both comedic and suspenseful moments. Shagwolf's awareness of his dual identity creates humorous interactions with the gang, especially Scooby, who may struggle to understand Shaggy's perspective. Shaggy's crush on Bridget adds a romantic subplot, creating amusing situations as he attempts to impress her while navigating the challenges of mystery-solving. His clumsy and endearing attempts at romance become a source of humor within the group. Shaggy's fondness for the Gypsy Moths introduces occasional nostalgic flashbacks to his childhood, exploring the origins of his love for baseball and mysteries. These flashbacks provide insights into Shaggy's character and contribute to the overall charm of the series. Despite his cowardly nature, Shaggy occasionally displays unexpected courage, especially when his friends are in danger. These moments highlight Shaggy's loyalty and the depth of his friendships within the Mystery Gang. Shaggy and Scooby's comedic chemistry remains a central aspect of the series, with their banter and antics providing laughter and levity throughout the mysteries. The duo's unique dynamic continues to be a fan-favorite element, showcasing their deep bond and shared love for adventure.
 * Walden "Wally" Rogers (voiced by Will Forte): Shaggy's cousin, and the owner of Ruffy. While he is just as cowardly as Shaggy, he appears as the "Steve Urkel" of the group. He is the nerdy and inventive yet clumsy and accident-prone member of the team, and could invent gadgets to help solve mysteries. Every time he creates an accident, he would say his main catchphrase "Did I do that?". He is also very clever and wisecracking, and would act as a comic relief like Bridget. Sometimes when his inventions goes awry or out of control, he would say "That wasn't supposed to happen." (just like Widget from "Wow! Wow! Wubbzy!"). He feels that he is too clumsy to help out with his team, but he is always willing to try his best no matter what. Wally is very capable with technology, gadgets, and other sorts of gizmos. He also appears to be an excellent builder and mechanic. His other catchphrases are "Whoa, Mama!" and "Yipes!". Wally's inventiveness extends beyond mystery-solving gadgets; he's also a whiz at creating quirky contraptions that add a comedic touch to the gang's adventures. Despite his clumsiness, his inventions occasionally become instrumental in solving mysteries, surprising everyone with their unexpected usefulness. Wally's clumsiness and catchphrase "Did I do that?" often lead to comedic situations, providing a light-hearted atmosphere during tense moments in the mysteries. His humorous mishaps create a running gag within the group, with other members playfully teasing him whenever something goes awry. While Wally doubts his own contributions, the rest of the gang values his unique skills and perspective, recognizing that his inventions and ideas often play a crucial role in cracking the case. His camaraderie with Shaggy adds a dynamic duo element to the team, as they navigate mysteries with a mix of humor and inventive problem-solving. Wally's proficiency in mechanics and building makes him the go-to person for repairing the Mystery Machine or crafting specialized equipment for the gang's investigations. His love for tinkering often leads to gadget upgrades, enhancing the team's capabilities over time. Despite his comedic persona, Wally occasionally imparts unexpected wisdom to the gang, drawing from his experiences with inventions and mishaps. His accidental insights may become valuable life lessons for the team, reminding them that mistakes can sometimes lead to unexpected successes. Wally could have recurring catchphrases related to his inventions, creating a humorous motif throughout the series. The gang might playfully wager on the likelihood of Wally's inventions going haywire, turning it into a recurring subplot.
 * Fred Jones (voiced by Robbie Amell): The leader of the Scooby-Doo Mystery Gang. Like in most incarnations, Fred usually takes the lead in solving mysteries. Although generally a very nice guy, Fred can be bossy at times forcing Shaggy and Scooby to take part in nabbing the villain despite their fears and/or better judgment. He is a control freak and takes mysteries overly seriously as the be all and end all. Because of the burden of leadership placed on him, and expects the others to follow his lead. He loves making plans, going on adventures, creating booby traps and solving mysteries. He also appears to have a crush on Daphne. His main catchphrases are "Let's split up, gang!" and "Hold the phone!". Fred's talent for planning and creating elaborate booby traps becomes an iconic aspect of the gang's investigative approach. His strategic mind adds a layer of suspense and excitement to the mysteries, showcasing his dedication to solving each case. Fred's love for adventures extends beyond solving mysteries, leading the gang to explore diverse locations and encounter a wide range of intriguing scenarios. His enthusiasm for the unknown fuels the gang's sense of exploration and discovery. While Fred can be perceived as a control freak, moments of vulnerability and understanding reveal a more compassionate side to his leadership style. He learns to balance his desire for control with acknowledging the strengths of each team member, fostering a stronger sense of unity within the gang. The challenges Fred faces as the leader are explored in more depth, shedding light on the personal sacrifices he makes for the well-being of the Mystery Gang. Moments of self-reflection and occasional doubts add layers to Fred's character, making him more relatable to the audience. Fred's crush on Daphne becomes a central theme, with their romantic tension adding a touch of drama and humor to the group dynamics. The evolving nature of their relationship is explored, creating moments of both heartwarming connection and comedic misunderstandings. Fred's catchphrases "Let's split up, gang!" and "Hold the phone!" evolve in creative ways, adapting to different situations and providing a sense of continuity throughout the series. These catchphrases become rallying cries for the gang, emphasizing Fred's role as a motivator and leader. Fred's leadership role includes navigating conflicts within the group, showcasing his skills in conflict resolution and ensuring a harmonious working relationship. His ability to unite the team during challenging moments becomes a testament to his leadership qualities.
 * Riff Jones (voiced by Zac Efron): Fred's twin brother, and the self-proclaimed jock and brawn of the group. Riff is like a strong and athletic leader, and acts as Fred's second-in-command. He also shares traits from Flim-Flam (a character from "The 13 Ghosts of Scooby-Doo" and "Scooby-Doo and the Curse of the 13th Ghost"). Unlike Fred, Riff is depicted as being somewhat less intelligent and often believes in crazy conspiracy theories and legends such as Bigfoot and mole people and reads the magazine The National Exaggerator (much like Freddy in A Pup Named Scooby-Doo). He is mainly interested in sports, martial arts, wrestling, and weightlifting. His ideas help the Gang gather the 13 ghosts (which Tom, Jerry, Sylvester and Tweety accidentally freed) and put them back into the chest. He is rivals with Red Herring (a returning character from A Pup Named Scooby-Doo), and likes to blame the mysteries on him. His main catchphrases are "Right on, man!" and "Holy cow!". Riff's physical strength and athleticism make him the powerhouse of the Mystery Gang, excelling in sports, martial arts, wrestling, and weightlifting. He occasionally showcases his impressive skills during action-packed moments, contributing to the gang's success in capturing villains. Riff's belief in conspiracy theories and legends adds a unique dynamic to the group, as he often suggests unconventional explanations for mysteries. The gang humorously navigates his wild theories, with Velma acting as the voice of reason and guiding them toward logical solutions. Riff's subscription to "The National Exaggerator" becomes a recurring subplot, providing the gang with leads on mysterious occurrences while adding a touch of humor. His magazine readings sometimes lead the gang to investigate unconventional cases, making for entertaining and unexpected adventures. Riff's playful rivalry with Red Herring introduces friendly competition within the group, with both characters vying for the spotlight in solving mysteries. Despite their rivalry, they occasionally team up to outsmart villains, showcasing moments of unexpected collaboration. Riff's strategic thinking, honed from his interest in sports, becomes a valuable asset during mysteries, allowing the gang to approach situations with a mix of physical and mental agility. His athletic prowess often aids the gang in navigating obstacles and chasing down villains. Riff's role as Fred's twin brother adds depth to their dynamic, with Fred relying on Riff's physical strength while Riff looks up to Fred's leadership and intelligence. Their interactions showcase a balance of brawn and brains within the team, highlighting the importance of diverse skills.
 * Daphne Blake (voiced by Kate Melton): The vain and fashionable one of the group. Like in most incarnations, Daphne is portrayed as the beautiful, enthusiastic, and eager to help, but occasionally clumsy and danger-prone member of the gang (hence her nickname, "Danger-prone Daphne") who follows her intuition. She sometimes serves as the damsel in distress and would occasionally get kidnapped, tied up, and then left imprisoned. However, she is also a wealthy woman with a haughty and sarcastic personality, and is not fond of getting dirty (just like her child counterpart in A Pup Named Scooby Doo). She has a butler named Jenkins. She also has a bigger interest in fashion and shopping in this series, and can be pretty vain at times. She also appears to have a crush on Fred. Her main catchphrase is "Jeepers!". Daphne's passion for fashion is explored in more depth, with each mystery location providing an opportunity for her to showcase stylish and thematic outfits. Her keen sense of style becomes a recurring subplot, adding a touch of glamour to the gang's adventures. Daphne's wealthy background is integrated into the series, allowing for occasional episodes that delve into her glamorous lifestyle and connections. Her resourcefulness and ability to access high-society events become valuable assets in solving mysteries. Daphne's sarcastic and haughty personality adds a layer of humor to the group dynamics, especially in moments where her fashionable sensibilities clash with the more rugged aspects of mystery-solving. Her witty remarks become a source of comic relief, creating a dynamic interplay with the other members of the gang. Jenkins, Daphne's butler, provides opportunities for comedic interactions and additional storylines, serving as both a guardian figure and a source of lighthearted banter. Jenkins' loyalty and commitment to Daphne contribute to the overall charm of the Mystery Gang's extended family. Daphne's intuitive nature is showcased alongside her fashion-forward persona, demonstrating that her insights go beyond her stylish exterior. She actively contributes to solving mysteries, using her intuition to uncover important clues and connections. Daphne's crush on Fred is explored in a more nuanced way, with moments of romantic tension and camaraderie adding depth to their relationship. The evolving dynamics between Daphne and Fred become a recurring theme, providing both heartfelt moments and comedic misunderstandings. While Daphne occasionally finds herself in perilous situations, these moments are balanced with instances where she takes charge and showcases her resilience. Her growth as a character includes overcoming the "damsel in distress" stereotype, highlighting her strengths and determination.
 * Bridget Blake (voiced by Amanda Seyfried): Daphne's twin sister, and the oddball of the team. She has the same personality as Daphne's "Be Cool, Scooby-Doo" counterpart. Unlike Daphne, Bridget is outgoing, quirky and comical. She is also the comic relief of the team. She is always trying something new that might make her seem "kooky" on the surface. It is almost as if she is trying to find her role in the Mystery Gang, and she actually has a list of things to try. However, this seemingly random aspect of her personality can be an annoyance to leader, Fred. He gets quite annoyed with her at times, while she doesn't see anything wrong with it. Occasionally, if he doesn't see it as likely to cause a problem, he will tolerable her quirks, such as letting her roller skate as his assistant in a magic act. Velma doesn't think it's a good idea to indulge her by acknowledging what she is doing. She has even wanted to avoid her altogether when splitting up. Velma will call out crazy or illegal quirks, such as when Bridget thought she could qualify as a lawyer by completing a video game. Despite these "flaws", she is always there to perk the Mystery Gang up as a metaphorical cheerleader, or on one occasion a mascot. When everyone has doubts about being able to solve the mystery they are on, she is able to point out how important everyone is and remind them of their respective roles. She appears to have a crush on Shaggy. She also has traits from Shannon Blake (a character from "Scooby-Doo and the Loch Ness Monster"). Despite her kooky personality, Bridget possesses a kind personality. She is very friendly, polite, and levelheaded, while also possessing pride in her heritage and a love of history, drama, puppets and gymnastics. She is very close with her twin sister Daphne, with whom she shares some personality traits with. She has been shown to possess a similar taste in fashion to Daphne, however, she is not quite as uptight about her clothing as Daphne is. Her main catchphrases are "What a hoot!" and "Gazooks!". Bridget's list of eccentric activities becomes a recurring theme, showcasing her adventurous and experimental nature within the Mystery Gang. The gang occasionally finds themselves unwittingly involved in Bridget's quirky pursuits, leading to both amusing and unexpected outcomes. Bridget's positive and uplifting attitude makes her the team's unofficial cheerleader, boosting morale during challenging investigations. She has an uncanny ability to highlight the strengths of each team member, fostering a supportive environment within the group. On certain missions, Bridget takes on the role of a metaphorical mascot, donning costumes or using props to inspire the gang and lighten the mood. Her creative and unconventional approach to problem-solving adds a unique flair to the team's dynamics. Bridget's wild and sometimes impractical ideas often clash with Velma's logical thinking, leading to humorous interactions and debates within the group. Despite Velma's skepticism, Bridget's unconventional methods occasionally yield unexpected insights that contribute to solving mysteries. Bridget's crush on Shaggy adds a touch of romantic tension within the group, creating amusing moments as she navigates her feelings while remaining an integral part of the team. Her attempts to impress Shaggy often lead to comedic situations, providing light-hearted moments in the midst of mysteries. Bridget's pride in her heritage and love of history, drama, puppets, and gymnastics add layers to her character, showcasing a well-rounded and diverse set of interests. These interests occasionally become valuable assets during investigations, where her knowledge and skills unexpectedly contribute to solving mysteries. Bridget's close relationship with Daphne serves as a grounding element, providing moments of sisterly support and understanding amidst the chaos of mystery-solving. Their interactions highlight the contrast between Daphne's elegance and Bridget's quirkiness, creating a harmonious balance within the Mystery Gang.
 * Velma Dinkley (voiced by Hayley Kiyoko); The brains of the team. Her personality is a mix of those of both her "Scooby-Doo Mystery Incorporated" and "Be Cool, Scooby-Doo" counterparts. Like in most incarnations, Velma is usually portrayed as a highly intelligent young woman with an interest in the sciences. She is also often portrayed as being very well-read on obscure fields such as Norse writing. Due to her intelligence and problem-solving abilities, Velma is typically the first one to solve the mystery and, like Sherlock Holmes and many other fictional detectives, often keeps her conclusions secret till the end of the story. Velma is characterized as the most skeptical of the gang and is most likely to discount any paranormal explanations to their mysteries. Velma's main catchphrase is "Jinkies", which she says when spooked, excited, discovered something or a clue, and during many other occasions. She is implied to be Jewish: she listens to Klezmer music, and frequently exclaims "Oy" and "Oy gevalt". She also has a case of coulrophobia (a fear of clowns) due to what happened on her fifth birthday. Velma's interest in Norse writing becomes a recurring theme, with mysteries occasionally tying back to ancient Norse legends and artifacts. Her knowledge in this field proves crucial in solving cases, adding a unique intellectual layer to the group's investigations. Velma harbors a secret passion for mystery writing, occasionally jotting down her own detective stories inspired by the gang's adventures. This subplot allows for moments where Velma's deductive skills are put to the test in crafting compelling mysteries for her fictional characters. Velma's proficiency with technology is highlighted, showcasing her ability to use gadgets and computers for investigative purposes. She occasionally invents new gadgets that aid the gang in solving mysteries, adding a modern twist to her problem-solving repertoire. Velma's eclectic taste in music, including Klezmer, adds cultural depth to her character, with occasional references to her favorite artists and genres. These references become a source of lighthearted moments and opportunities for the gang to bond over their diverse interests. Velma's occasional moments of clumsiness or humorous reactions provide comic relief, balancing her serious and studious demeanor. The juxtaposition of her intellectual prowess with moments of levity adds to the overall charm of the Mystery Gang. Velma's relationship with her younger sister, Madelyn, is explored, showcasing a mix of protective instincts and humorous sibling dynamics. Madelyn's whimsical personality contrasts with Velma's logical approach, creating entertaining interactions within the Mystery Gang. Velma's fear of clowns becomes a character arc, with moments of facing and overcoming this fear, leading to personal growth. This subplot adds a touch of vulnerability to Velma's character, making her even more relatable to the audience.
 * Madelyn Dinkley (voiced by Gina Rodriguez); An exclusive character from "Scooby-Doo: Abracadabra-Doo", who is Velma's younger sister (now only a year younger in this version). Her personality is similar to Kusama from Teenage Mutant Ninja Heroes, Bubbles from Jabberjaw and Melody from Josie and the Pussycats, making her the slightly ditzy, whimsical, quirky and unconventional yet kind and innocent member of the group. She may be somewhat ditzy and bipolar, and can mess things up sometimes, but there are times when she is actually pretty smart, helpful, and a quick thinker and learner too. She is also shy and soft-spoken at times. She also has a special sixth sense, and can predict what happens before or after. Madelyn is the opposite of her big sister, Madelyn seems more extroverted, while Velma is more introverted. Velma and Madelyn love each other more than anything and are very protective of one another, but Velma can't stand Madelyn's tendency to make rash choices and often rubs it in her face. But overall, they still love each other as sisters. She appears to be excellent in magic tricks and loves reading mystic and mythology books. Her main catchphrase is "Mysteries are magical!". Madelyn's whimsical and quirky nature adds a delightful and unpredictable element to the Mystery Gang, bringing a touch of magic to their adventures. Her unconventional thinking often leads to surprising solutions and discoveries during investigations. Madelyn's occasional ditzy moments belie her underlying intelligence. She possesses a unique blend of whimsy and quick thinking that aids the gang in unexpected ways. Her ability to see patterns and connections others might overlook becomes a valuable asset during mysteries. Madelyn's special sixth sense and proficiency in magic tricks contribute to the supernatural aspects of the mysteries. Her predictions, while sometimes cryptic, serve as essential clues that guide the gang in the right direction. The contrast between Madelyn's extroverted, mystical personality and Velma's introverted, logical nature creates a dynamic sisterly relationship. Their interactions showcase moments of love, support, and occasional sibling rivalry, adding depth to both characters. Madelyn's protective instincts toward Velma mirror Velma's protective nature towards her younger sister, creating a heartwarming and endearing dynamic within the group. Madelyn's love for mystic and mythology books becomes a recurring theme, with her often referencing magical lore to provide insights into the mysteries they encounter. Her proficiency in magic tricks adds a touch of theatricality to the gang's investigations, making for visually engaging and entertaining moments. Madelyn's shy and soft-spoken demeanor creates moments of vulnerability, balancing her whimsical persona with a more reserved side that the gang respects and supports. Madelyn's catchphrase, "Mysteries are magical!", becomes a signature line that encapsulates her fascination with the supernatural and her belief in the enchanting nature of their detective work.
 * Tom Cat (voiced by Josh Brener): One of the animal members of the Mystery Gang. Like most of his incarnations, he likes to chase Jerry. He usually speaks in clear English (like his counterpart from "Tom and Jerry: The Movie (1992)"). He can be a bit cowardly, even when Shaggy turns into Shagwolf (hence the reason why he has so many umbrella hats to pretend he's an umbrella, hoping Shagwolf won't find him). He and Jerry put their differences behind them and help their friends solve mysteries. Tom is usually convinced by "Tom Treats" like Scooby is with "Scooby Snacks". Just like Riff, Tom has a rivalry with Spike the Bulldog, and likes to blame the mysteries on him. His main catchphrases are "Meowza!", and "Don't you believe it!".
 * Jerry Mouse (voiced by Stephanie Nadolny): One of the animal members of the Mystery Gang. Jerry is remade into a female mouse. Like her counterpart from 1992's Tom and Jerry: The Movie, she can also talk in English. Jerry helps Fred with the trap-making like she did with Tom. Jerry is a quick-thinker and knows what to do, even when the traps didn't go according to plan. Her favorite snacks are "Jerry Bites". Her main catchphrases are "Holy Cheese!" and "Geronimo!".
 * Sylvester Cat (voiced by Eric Bauza): One of the animal members of the Mystery Gang, and is made as Tom's cousin. He is mainly based on his counterpart from "The Sylvester & Tweety Mysteries". Like in other incarnations, Sylvester continually tries to devour Tweety for his supper, though he is always thwarted by Hector or Tweety's craftiness. Despite their never-ending feud, the pair manage to get along for the most part and help the others solve mysteries, and Sylvester will defend Tweety when someone else tries to harm the canary. Sylvester also unwittingly discovers many clues, claiming as the narrator to have knowledge of the case (though this is probably bluster). Besides chasing Tweety, Sylvester often explores the surroundings, leading him to sometimes be in awkward situations (i.e. being chased by a male cousin of Pepe Le Pew, Pitu Le Pew or using Granny's umbrella to pierce a villain's blimp). Through these situations, the baritone and tenor singing, lisping Tuxedo cat endures all manner of pain and suffering, but comes out none the worse for wear. Sylvester is allergic to wool and is jealous of Tweety. Sylvester and Tom are very close cousins/best friends, and like to share with each other. His favorite snacks are "Sylvester Snacks". His main catchphrases are "Sufferin' Succotash!" and "Oh my whiskers!".
 * Tweety Bird (voiced by Kate Miccuci): One of the animal members of the Mystery Gang, and is depicted to be best friends with Jerry in this series. Like Jerry, Tweety is now a cute but mischievous female yellow canary. She is mainly based on her counterpart from "The Sylvester & Tweety Mysteries". As always, Tweety is often trying to escape Sylvester by foiling him through either her flying, clever timing, or her bodyguard Hector the Bulldog. Tweety usually stays with Granny and is responsible for some major clues. Despite her feud with Sylvester, the pair will sometimes get along and team up if Granny or any of their team is threatened and can work together very well. Tweety also serves as a source of ironic humor at times, usually in reference to Sylvester's foiled attempts to eat her. Tweety also gets along with Jerry, and the two little critters can always find a way to trap disguised villains while trying to escape Tom and Sylvester. Her favorite snacks are "Tweety Clusters". Her main catchphrase is "I tawt I taw a puddy tat!".
 * Emma "Granny" Webster (voiced by Candi Milo): A practical old-fashioned world-renowned detective who acts as a mentor of sorts to the Mystery Gang. Granny travels the globe with the Gang, attending events such as races or canary contest and is often called upon by the locals to solve a crime. However, there have been attempts to frame Granny, causing some difficulty in finding clues. She is overprotective of Tweety, and will not hesitate to give Sylvester a good whack on the head. She sometimes calls upon the cat to investigate clues or defend the group while they sleep, though, showing signs of obvious trust. Granny is good natured mostly, but can become stern.
 * Hector the Bulldog (voiced by John DiMaggio): Granny's pet bulldog and Tweety's bodyguard. Hector usually keeps Sylvester from eating the canary and will often beat him up if he gets in his way. Hector will defend Granny or the Mystery Gang (even Sylvester) if threatened, but is not above stealing food or trying to please others.

Secondary Characters

 * Jabberjaw (voiced by ):
 * Speed Buggy (voiced by ):
 * Captain Caveman (voiced by ):
 * Angel Dynamite/Cassidy Williams (voiced by ):
 * Principal Quinlan (voiced by ):
 * Jonathan Wellington "Mudsy" Muddlemore (voiced by ):
 * Bugs Bunny (voiced by ):
 * Lola Bunny (voiced by ):
 * Woofer (voiced by ):
 * Wimper (voiced by ):

Musical Instruments

 * Scooby: Lead Guitarist
 * Ruffy: Saxophonist
 * Shaggy: Bassist
 * Wally: Trumpeter
 * Fred: Drummer
 * Riff: Percussionist (Congas)
 * Daphne: Keyboardist
 * Bridget: Theremin Player
 * Velma: Lead Singer
 * Madelyn: Flutist

Season 1

 * 1) Mystery at the Haunted Carnival: The gang attends a local carnival, only to discover it's haunted by a ghostly figure. Unravel the mystery behind the spooky occurrences and the carnival's history.
 * 2) Phantom of the Opera House: The gang gets involved in a mystery surrounding an old opera house where a phantom is rumored to be haunting performances. Is it a disgruntled actor or something more supernatural?
 * 3) Time-Traveling Terrors: The Mystery Machine accidentally stumbles upon a time portal, leading the gang to different historical periods where they encounter ghosts and mysteries tied to each era.
 * 4) Cryptozoological Conundrum: The gang visits a remote town where locals claim sightings of mythical creatures. Investigate the mysterious occurrences and determine if there's any truth to the legends.
 * 5) Ghost Ship Galore: A mysterious ghost ship appears in the harbor, and the gang must uncover the connection between the ship, its spectral crew, and a long-lost treasure.
 * 6) Alien Antics at Area 51: While passing through the desert, the gang stumbles upon Area 51 and discovers strange occurrences. Uncover the truth behind the extraterrestrial rumors and government secrets.
 * 7) Enchanted Amusement Park: The gang visits an amusement park with enchanted rides, leading to bizarre and supernatural experiences. Solve the mystery behind the park's magical anomalies.
 * 8) Haunted Hollywood: The gang gets invited to a movie set where strange events are jeopardizing the film production. Investigate the behind-the-scenes mystery and save the movie.

Trivia

 * This series has some elements and inspirations from other mystery cartoons like The Funky Phantom, Clue Club, and The Sylvester & Tweety Mysteries.
 * This show include a new voice cast instead of the original cast, and it also includes five new main characters who are the new members of the Mystery Inc. crew.
 * It is also a crossover series with Tom & Jerry and Looney Tunes.